Table 1.

Influence of IL-7 on macrophage and NK cell growth from DN1 and DN2 cells



Macrophage colonies,*%

NK cell colonies,%

With IL-7
Without IL-7
Without IL-7, but with anti-IL-7Rα mAb
With IL-7
Without IL-7
Without IL-7, but with anti-IL-7Rα mAb
DN1   100  90   64   100  92   87  
DN2
 
100
 
50
 
13
 
100
 
98
 
69
 


Macrophage colonies,*%

NK cell colonies,%

With IL-7
Without IL-7
Without IL-7, but with anti-IL-7Rα mAb
With IL-7
Without IL-7
Without IL-7, but with anti-IL-7Rα mAb
DN1   100  90   64   100  92   87  
DN2
 
100
 
50
 
13
 
100
 
98
 
69
 
*

Macrophage growth was assessed on ST-2 stromal cells.

NK cell growth was assessed on OP9 stromal cells; all cultures also contained IL-2.

Numbers of macrophage or NK cell colonies in culture with IL-7 were normalized to 100%.

Close Modal

or Create an Account

Close Modal
Close Modal