Table 3.

Effect of adaphostin on level of Bcl-2 in CLL B-cells


Adaphostin concentration (μM)

Patient A

Patient B
0   526   275  
1.25   400   225  
2.5   369   176  
5   261   150  
10   214   163  
20
 
223
 
134
 

Adaphostin concentration (μM)

Patient A

Patient B
0   526   275  
1.25   400   225  
2.5   369   176  
5   261   150  
10   214   163  
20
 
223
 
134
 

Mean fluorescent values of Bcl-2 in CLL B cells treated with increasing doses of adaphostin.

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