Table 1. Details of patients with CLL... | American Society of Hematology

Table 1.

Details of patients with CLL with secondary AIHA (CLL + AIHA)

						Autoantibody specificity			Splenomegaly, Rai stage/splenomegaly, length below costal margin		Blood counts at diagnosis and at sampling
Patient	Sex	Age, y	RhD +/-	Coombs IgG	Coombs C3	Rh	Pan-agglutinin			CLL/AIHA duration, mo	Hb, g/L	WBC, 10⁹/L	Platelets, 10⁹/L	Previous therapy	Current therapy, mg/d
1	M	66	+	+++++	-	Y	N	II/Tip	24/24	50	590	100	Chlorambucil, CHOP	Prednisolone, 5
										113	6.7	138
2	M	73	+	+++++	+++++	Y	N	III/-	18/8	62	5.9	193	Chlorambucil	Prednisolone, 5; Azathioprine, 100
										142	42	90
3	M	75	+	++++	++	Y	N	I/-	3/3	83	159	228	None	Prednisolone, 7.5
										114	63	206
4	F	83	+	+++++	-	Y	N	0/-	1/1	90	10.7	195	None	Prednisolone, 40
										96	12.8	220
5	M	87	+	+	-	Y	N	II/2 cm	48/48	51	35.5	53	None	Prednisolone, 40
										84	57	99
6	M	68	+	+	+	Y	N	IV/6 cm	4/2	68	366	111	Chlorambucil	Prednisolone, 20
										97	166	53
7	M	69	-	+++	++	Y	Y	IV/-	20/16	40	240	331	Chlorambucil, CHOP, etoposide, 2 courses fludaribine 15/12 presampling	Prednisolone, 80
										79	339	130
8	F	82	-	+++	++	Y	Y	I/-	98/11	78	137	46	Chlorambucil	Prednisolone, 5
										119	15.5	213
9	M	68	+	++	++	UA	UA	II/-	42/36	111	98	205	Chlorambucil	Chlorambucil, 2.5
										134	14.1	161
10	M	74	+	++	++	UA	UA	I/-	43/1	72	78.8	260	None	Prednisolone, 30
										111	83.4	312
11	M	70	+	+++	++	UA	UA	IV/6 cm	74/9	48	208	32	Chlorambucil Fludarabine 2 courses 2 mo previously	Prednisolone, 60
										52	204	39
12	F	78	+	+++	-	UA	UA	II/5 cm	234/140	67	156	201	Prednisolone Azathioprine	None
										126	30.7	104

						Autoantibody specificity			Splenomegaly, Rai stage/splenomegaly, length below costal margin		Blood counts at diagnosis and at sampling
Patient	Sex	Age, y	RhD +/-	Coombs IgG	Coombs C3	Rh	Pan-agglutinin			CLL/AIHA duration, mo	Hb, g/L	WBC, 10⁹/L	Platelets, 10⁹/L	Previous therapy	Current therapy, mg/d
1	M	66	+	+++++	-	Y	N	II/Tip	24/24	50	590	100	Chlorambucil, CHOP	Prednisolone, 5
										113	6.7	138
2	M	73	+	+++++	+++++	Y	N	III/-	18/8	62	5.9	193	Chlorambucil	Prednisolone, 5; Azathioprine, 100
										142	42	90
3	M	75	+	++++	++	Y	N	I/-	3/3	83	159	228	None	Prednisolone, 7.5
										114	63	206
4	F	83	+	+++++	-	Y	N	0/-	1/1	90	10.7	195	None	Prednisolone, 40
										96	12.8	220
5	M	87	+	+	-	Y	N	II/2 cm	48/48	51	35.5	53	None	Prednisolone, 40
										84	57	99
6	M	68	+	+	+	Y	N	IV/6 cm	4/2	68	366	111	Chlorambucil	Prednisolone, 20
										97	166	53
7	M	69	-	+++	++	Y	Y	IV/-	20/16	40	240	331	Chlorambucil, CHOP, etoposide, 2 courses fludaribine 15/12 presampling	Prednisolone, 80
										79	339	130
8	F	82	-	+++	++	Y	Y	I/-	98/11	78	137	46	Chlorambucil	Prednisolone, 5
										119	15.5	213
9	M	68	+	++	++	UA	UA	II/-	42/36	111	98	205	Chlorambucil	Chlorambucil, 2.5
										134	14.1	161
10	M	74	+	++	++	UA	UA	I/-	43/1	72	78.8	260	None	Prednisolone, 30
										111	83.4	312
11	M	70	+	+++	++	UA	UA	IV/6 cm	74/9	48	208	32	Chlorambucil Fludarabine 2 courses 2 mo previously	Prednisolone, 60
										52	204	39
12	F	78	+	+++	-	UA	UA	II/5 cm	234/140	67	156	201	Prednisolone Azathioprine	None
										126	30.7	104

Hb indicates hemoglobin; +, positive; -, negative; Y, yes; N, no; Tip, just palpable; CHOP, cyclophosphamide, adriamycin, vincristine, and prednisolone; and UA, unavailable.

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