Table 5. Multivariate analysis of TRM... | American Society of Hematology

Table 5.

Multivariate analysis of TRM for patients 20 and older

Variables	N	Relative risk (95% CI)	P
0-3 mo after transplantation^*			< .001†
Japanese	562	1.00	NA
White American	805	2.99 (1.93-4.64)	< .001‡
African American	67	5.88 (3.08-11.20)	< .001‡
Scandinavian	188	1.03 (0.48-2.21)	.99‡
Irish	93	2.66 (1.28-5.54)	.009‡
More than 3 mo after transplantation			.26†
Japanese	524	1.00	NA
White American	683	1.09 (0.83-1.44)	.99‡
African American	51	1.08 (0.52-2.24)	.99‡
Scandinavian	176	0.64 (0.40-1.03)	.68‡
Irish	80	0.90 (0.48-1.68)	.99‡
Age at transplantation, y
20-40	935	1.00	NA
Older than 40	780	1.79 (1.46-2.18)	< .001
Disease type			.005§
CML	891	1.00	NA
ALL	268	1.51 (1.14-1.99)	.004
AML	556	0.94 (0.75-1.18)	.59

Variables	N	Relative risk (95% CI)	P
0-3 mo after transplantation^*			< .001†
Japanese	562	1.00	NA
White American	805	2.99 (1.93-4.64)	< .001‡
African American	67	5.88 (3.08-11.20)	< .001‡
Scandinavian	188	1.03 (0.48-2.21)	.99‡
Irish	93	2.66 (1.28-5.54)	.009‡
More than 3 mo after transplantation			.26†
Japanese	524	1.00	NA
White American	683	1.09 (0.83-1.44)	.99‡
African American	51	1.08 (0.52-2.24)	.99‡
Scandinavian	176	0.64 (0.40-1.03)	.68‡
Irish	80	0.90 (0.48-1.68)	.99‡
Age at transplantation, y
20-40	935	1.00	NA
Older than 40	780	1.79 (1.46-2.18)	< .001
Disease type			.005§
CML	891	1.00	NA
ALL	268	1.51 (1.14-1.99)	.004
AML	556	0.94 (0.75-1.18)	.59

NA indicates not applicable.

Other significant comparisons:

Scandinavian vs white American (less than 3 months): RR = 0.35; 95% CI, 0.17-0.68; P = .022‡
Scandinavian vs African American (less than 3 months): RR = 0.18; 95% CI, 0.08-0.40; P < .001‡

Time-dependent covariate, such that risk for TRM varied before and 3 months after transplantation.

4 degrees of freedom test.

Adjusted for 10 multiple comparisons.

2 degrees of freedom test.