Table 5.

Possible mechanisms of responses to Cbl therapy



Laboratory tests
Category and mechanisms
Cbl
MMA/HCys
Vitamin deficient: decreased dietary intake and decreased absorption   Low   High  
Vitamin dependent: impaired transport, impaired coenzyme formation, abnormal apoenzymes, and Cbl inhibitors   Normal   High  
Vitamin responsive: pharmacologic effects on Cbl-related processes and Cbl-unrelated processes
 
Normal
 
Normal
 


Laboratory tests
Category and mechanisms
Cbl
MMA/HCys
Vitamin deficient: decreased dietary intake and decreased absorption   Low   High  
Vitamin dependent: impaired transport, impaired coenzyme formation, abnormal apoenzymes, and Cbl inhibitors   Normal   High  
Vitamin responsive: pharmacologic effects on Cbl-related processes and Cbl-unrelated processes
 
Normal
 
Normal
 
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