Possible mechanisms of responses to Cbl therapy
. | Laboratory tests . | . | |
---|---|---|---|
Category and mechanisms . | Cbl . | MMA/HCys . | |
Vitamin deficient: decreased dietary intake and decreased absorption | Low | High | |
Vitamin dependent: impaired transport, impaired coenzyme formation, abnormal apoenzymes, and Cbl inhibitors | Normal | High | |
Vitamin responsive: pharmacologic effects on Cbl-related processes and Cbl-unrelated processes | Normal | Normal |
. | Laboratory tests . | . | |
---|---|---|---|
Category and mechanisms . | Cbl . | MMA/HCys . | |
Vitamin deficient: decreased dietary intake and decreased absorption | Low | High | |
Vitamin dependent: impaired transport, impaired coenzyme formation, abnormal apoenzymes, and Cbl inhibitors | Normal | High | |
Vitamin responsive: pharmacologic effects on Cbl-related processes and Cbl-unrelated processes | Normal | Normal |