Table 1.

Cytotoxicity of cultured MMCs or cultured CTMCs derived from Balb/c+/+ or Balb/c-Stat4-deficient mice


Cytotoxic activity of cultured mast cells

Culture MMCs, % ± SEM

Cultured CTMCs, % ± SEM
Wild-type
Stat 4-KO
Wild-type
Stat 4-KO
Nonviable P815 cells   13.1 ± 1.3  4.7 ± 2.4*  47.2 ± 2.2*  10.4 ± 1.3 
Nonviable L929 cells
 
3.5 ± 1.9
 
5.2 ± 1.8
 
24.8 ± 1.8*
 
24.2 ± 4.5*
 

Cytotoxic activity of cultured mast cells

Culture MMCs, % ± SEM

Cultured CTMCs, % ± SEM
Wild-type
Stat 4-KO
Wild-type
Stat 4-KO
Nonviable P815 cells   13.1 ± 1.3  4.7 ± 2.4*  47.2 ± 2.2*  10.4 ± 1.3 
Nonviable L929 cells
 
3.5 ± 1.9
 
5.2 ± 1.8
 
24.8 ± 1.8*
 
24.2 ± 4.5*
 

Data are shown as percent plus or minus the standard error of the mean.

*

P < .05 by t test when compared with the value of cultured Balb/c+/+ MMCs.

P < .05 by t test when compared with the value of cultured Balb/c+/+ CTMCs.

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