Cytogenetic findings at the time of initial diagnosis (Dx) of MMM and at the time of LT, where available, in a cohort of 91 patients
. | Findings at Dx of MMM, no. (%) . | Findings at Dx of LT, no. (%) . |
|---|---|---|
| No. | 32 (100.0) | 56 (100.0) |
| Normal (NN) | 12 (37.5) | 5 (8.9) |
| 1 abnormality | 12 (37.5) | 17 (30.3) |
| 2 abnormalities | 2 (6.2) | 4 (7.2) |
| 3 or more abnormalities | 6 (18.8) | 30 (53.6) |
| Specific cytogenetic lesions at time of MMM diagnosis | ||
| 20q- | 4 (12.5) | — |
| 13q- | 1 (3.1) | — |
| +8 | 1 (3.1) | — |
| +9 | 4 (12.5) | — |
| 12p- | 3 (9.4) | — |
| -5/-7 | 2 (6.3) | — |
| Specific cytogenetic lesions at time of LT | ||
| Favorable | — | 2 (3.6) |
| t(8;21)(q22;q22) | — | 1 (1.8) |
| inv(16)(p13;q22) | — | 1 (1.8) |
| Intermediate | — | 20 (35.7) |
| High risk | — | 34 (60.7) |
| 3 or more abnormalities | — | 30 (53.6) |
| -5/5q- | — | 11 (26.8) |
| -7/7q- | — | 7 (19.6) |
| +8 | — | 14 (23.2) |
. | Findings at Dx of MMM, no. (%) . | Findings at Dx of LT, no. (%) . |
|---|---|---|
| No. | 32 (100.0) | 56 (100.0) |
| Normal (NN) | 12 (37.5) | 5 (8.9) |
| 1 abnormality | 12 (37.5) | 17 (30.3) |
| 2 abnormalities | 2 (6.2) | 4 (7.2) |
| 3 or more abnormalities | 6 (18.8) | 30 (53.6) |
| Specific cytogenetic lesions at time of MMM diagnosis | ||
| 20q- | 4 (12.5) | — |
| 13q- | 1 (3.1) | — |
| +8 | 1 (3.1) | — |
| +9 | 4 (12.5) | — |
| 12p- | 3 (9.4) | — |
| -5/-7 | 2 (6.3) | — |
| Specific cytogenetic lesions at time of LT | ||
| Favorable | — | 2 (3.6) |
| t(8;21)(q22;q22) | — | 1 (1.8) |
| inv(16)(p13;q22) | — | 1 (1.8) |
| Intermediate | — | 20 (35.7) |
| High risk | — | 34 (60.7) |
| 3 or more abnormalities | — | 30 (53.6) |
| -5/5q- | — | 11 (26.8) |
| -7/7q- | — | 7 (19.6) |
| +8 | — | 14 (23.2) |
— indicates not applicable.