Cytokine production profile of T(imm) and T(mat) cells
. | T(imm) . | T(mat) . | P . |
---|---|---|---|
IL-2, pg/mL | < 20 | 273.3 ± 79.8 | ≤ .009 |
IL-4, pg/mL | < 20 | 53.0 ± 6.2 | ≤ .007 |
IL-10, pg/mL | 500 ± 100 | 1400 ± 400 | ≤ .032 |
IFN-γ, ng/mL | 1.1 ± 0.5 | 10.7 ± 4.6 | ≤ .039 |
TGF-β, pg/mL | 95.0 ± 35.7 | 133.3 ± 11.2 | NS |
. | T(imm) . | T(mat) . | P . |
---|---|---|---|
IL-2, pg/mL | < 20 | 273.3 ± 79.8 | ≤ .009 |
IL-4, pg/mL | < 20 | 53.0 ± 6.2 | ≤ .007 |
IL-10, pg/mL | 500 ± 100 | 1400 ± 400 | ≤ .032 |
IFN-γ, ng/mL | 1.1 ± 0.5 | 10.7 ± 4.6 | ≤ .039 |
TGF-β, pg/mL | 95.0 ± 35.7 | 133.3 ± 11.2 | NS |
At the end of 3 rounds of stimulation with immature or mature DCs, T cells were activated with mature DCs, and supernatants were collected after 24 (for IL-2 and IL-4), 48 (for IL-10 and IFN-γ), or 72 (for TGF-β) hours, and levels of the indicated cytokines were determined by ELISA. Numbers represent the average ± SEM amounts detected in 6 independent experiments.