Ultrasound data from the SS cohort sample
Genotype . | Total N . | Gallstone-negative, n (% of total) . | Gallstone-positive, n (% of total) . | Average age at detection of gallstones, y (SD) . |
|---|---|---|---|---|
| 5/5 | 2 | 1 (50.0) | 1 (50.0) | 24.0 (0.0) |
| 5/6 | 22 | 14 (63.6) | 8 (36.4) | 15.1 (6.0) |
| 5/7 | 10 | 6 (60.0) | 4 (40.0) | 13.8 (7.4) |
| 6/6 | 56 | 37 (66.1) | 19 (33.9) | 15.6 (4.8) |
| 6/7 | 66 | 38 (57.6) | 28 (42.4) | 15.1 (3.9) |
| 6/8 | 1 | 0 (0.0) | 1 (100.0) | 10.0 (0.0) |
| 7/7 | 39 | 23 (59.0) | 16 (41.0) | 14.3 (5.0) |
| 7/8 | 6 | 1 (16.7) | 5 (83.3)* | 16.6 (5.3) |
Genotype . | Total N . | Gallstone-negative, n (% of total) . | Gallstone-positive, n (% of total) . | Average age at detection of gallstones, y (SD) . |
|---|---|---|---|---|
| 5/5 | 2 | 1 (50.0) | 1 (50.0) | 24.0 (0.0) |
| 5/6 | 22 | 14 (63.6) | 8 (36.4) | 15.1 (6.0) |
| 5/7 | 10 | 6 (60.0) | 4 (40.0) | 13.8 (7.4) |
| 6/6 | 56 | 37 (66.1) | 19 (33.9) | 15.6 (4.8) |
| 6/7 | 66 | 38 (57.6) | 28 (42.4) | 15.1 (3.9) |
| 6/8 | 1 | 0 (0.0) | 1 (100.0) | 10.0 (0.0) |
| 7/7 | 39 | 23 (59.0) | 16 (41.0) | 14.3 (5.0) |
| 7/8 | 6 | 1 (16.7) | 5 (83.3)* | 16.6 (5.3) |
Abdominal ultrasounds were performed annually in all SS cohort subjects, regardless of symptoms. Subjects within each genotype class were compared with those in the 6/6 wild type. P < .001 was regarded as significant after correction for multiple testing.
P < .03.