Table 4. Ploidy distribution of CD41 MK... | American Society of Hematology

Table 4.

Ploidy distribution of CD41⁺ MK cells derived from healthy subjects and patients with MMM with and without anti-CXCR1 and anti-CXCR2 antibodies

		2n ploidy			4n ploidy
	Lower than 2n ploidy, sub-G₁ phase, %	%	S phase %	%	S phase %	Greater than 8n ploidy, %
NPB
Control	28±3	61±2	36±1	25±0	43±3	14±2
Anti-CXCR1	22±5	58±3	25±5	27±0	39±10	15±2
Anti-CXCR2	21±6	61±5	26±6	26±1	41±4	14±2
MMM16
Control	43	69	80	26	60	5
Anti-CXCR1	33	63	31	24	40	13
Anti-CXCR2	24	53	40	32	45	15
MMM17
Control	40	83	57	15	18	2
Anti-CXCR1	3	69	31	23	26	8
Anti-CXCR2	ND	ND	ND	ND	ND	ND
MMM18
Control	29	64	55	27	45	9
Anti-CXCR1	19	62	38	22	28	16
Anti-CXCR2	19	57	33	26	35	17

		2n ploidy			4n ploidy
	Lower than 2n ploidy, sub-G₁ phase, %	%	S phase %	%	S phase %	Greater than 8n ploidy, %
NPB
Control	28±3	61±2	36±1	25±0	43±3	14±2
Anti-CXCR1	22±5	58±3	25±5	27±0	39±10	15±2
Anti-CXCR2	21±6	61±5	26±6	26±1	41±4	14±2
MMM16
Control	43	69	80	26	60	5
Anti-CXCR1	33	63	31	24	40	13
Anti-CXCR2	24	53	40	32	45	15
MMM17
Control	40	83	57	15	18	2
Anti-CXCR1	3	69	31	23	26	8
Anti-CXCR2	ND	ND	ND	ND	ND	ND
MMM18
Control	29	64	55	27	45	9
Anti-CXCR1	19	62	38	22	28	16
Anti-CXCR2	19	57	33	26	35	17

Data for healthy subjects are the mean of 3 distinct experiments; data for MMM subjects are presented individually. See Table 3 for abbreviations.