CEP-701 sensitivity by FLT3 expression level and cytogenetics
. | Sensitive . | Resistant . | % Sensitive . | P, versus low . |
|---|---|---|---|---|
| FLT3-low | 1 | 12 | 8 | — |
| FLT3-high | 17 | 6 | 74 | .0003* |
| MLL | 9 | 2 | 82 | .0005* |
| High hyper | 5 | 0 | 100 | .0007* |
| Other | 3 | 4 | 43 | .1011 |
. | Sensitive . | Resistant . | % Sensitive . | P, versus low . |
|---|---|---|---|---|
| FLT3-low | 1 | 12 | 8 | — |
| FLT3-high | 17 | 6 | 74 | .0003* |
| MLL | 9 | 2 | 82 | .0005* |
| High hyper | 5 | 0 | 100 | .0007* |
| Other | 3 | 4 | 43 | .1011 |
P value determined by Fisher exact test.
—Indicates comparison not possible; MMLL, samples with rearranged MLL gene; High hyper, samples with hyperdiploidy (> 50 chromosomes); Other, samples with normal cytogenetics or other abnormalities (see Table 2).
Significant