Table 6. Characteristics of randomized... | American Society of Hematology

Table 6.

Characteristics of randomized patients

	R1			R2			R3 + R4
	MTX-4h	MTX-24h	MTX-4h	MTX-24h	MTX-4h	MTX-24h	MTX-4h	MTX-24h
No. patients	21	19	93	96	66	69	180	184
No. male	18	13	68	72	54	52	140	137
No. female	3	6	25	24	12	17	40	47
Median age, y	10.9	9.8	9.0	9.3	8.6	7.7	8.7	8.8
Age 10 years or older, no.	12	8	40	43	24	19	76	70
Burkitt, no.	16	12	53	67	53	55	122	134
DLBL, no.	4	6	27	23	5	6	36	35
Other, no.	1	1	13	6	8	8	22	15
Stage, no.
I	9	6	12	12	0	0	21	18
II	12	13	36	40	0	0	48	53
III	0	0	45	44	39	32	84	76
IV, CNS^-	0	0	0	0	5	8	5	8
IV, CNS⁺	0	0	0	0	2	9	2	9
B-AL, CNS^-	0	0	0	0	13	17	13	17
B-AL, CNS⁺	0	0	0	0	7	3	7	3
Median LDH, U/L	206	212	248	234	1,036	883	348	308
LDH 1000 U/L or more, no.	0	0	0	0	34	31	34	31
Vital tumor at SL-OP, no.	NA	NA	1^*	1†	1‡	0	2	1
Risk group R4 patients, no.	NA	NA	NA	NA	40	38	40	38

	R1			R2			R3 + R4
	MTX-4h	MTX-24h	MTX-4h	MTX-24h	MTX-4h	MTX-24h	MTX-4h	MTX-24h
No. patients	21	19	93	96	66	69	180	184
No. male	18	13	68	72	54	52	140	137
No. female	3	6	25	24	12	17	40	47
Median age, y	10.9	9.8	9.0	9.3	8.6	7.7	8.7	8.8
Age 10 years or older, no.	12	8	40	43	24	19	76	70
Burkitt, no.	16	12	53	67	53	55	122	134
DLBL, no.	4	6	27	23	5	6	36	35
Other, no.	1	1	13	6	8	8	22	15
Stage, no.
I	9	6	12	12	0	0	21	18
II	12	13	36	40	0	0	48	53
III	0	0	45	44	39	32	84	76
IV, CNS^-	0	0	0	0	5	8	5	8
IV, CNS⁺	0	0	0	0	2	9	2	9
B-AL, CNS^-	0	0	0	0	13	17	13	17
B-AL, CNS⁺	0	0	0	0	7	3	7	3
Median LDH, U/L	206	212	248	234	1,036	883	348	308
LDH 1000 U/L or more, no.	0	0	0	0	34	31	34	31
Vital tumor at SL-OP, no.	NA	NA	1^*	1†	1‡	0	2	1
Risk group R4 patients, no.	NA	NA	NA	NA	40	38	40	38

NA indicates not applicable; SL-OP, second look—operation.

Alive disease-free after autologous stem cell transplantation.

Died of progressive disease after autologous stem cell transplantation.

Alive disease-free after autologous stem cell transplantation.