Table 2.

Highly expressed genes in ATL cells compared with normal CD4+ and CD4+CD45RO+ T cells

Fold change
Accession no.
Symbol
Gene
CD4+
CD45RO+
AF070648  CAV1  Caveolin 1*  34.82   49.74  
AF150241  PGDS  Prostaglandin D2 synthase   31.21   12.56  
AL080181  TSLC1  Tumor suppressor in lung cancer 1   30.36   36.86  
M36711  TFAP2A  Transcription factor AP-2 alpha   19.14   11.28  
AF079529  PDE8B  Phosphodiesterase 8B   17.58   13.07  
AB002305  ARNT2  Aryl-hydrocarbon receptor nuclear translocator 2   17.15   22.59  
X58288  PTPRM  Protein tyrosine phosphatase, receptor type, M   15.89   5.12  
Y00664  NMYC  V-myc myelocytomatosis viral related oncogene, neuroblastoma   15.30   12.11  
J03802  PTHLH  Parathyroid hormone-like hormone*†  14.10   8.68  
AF022797  KCNN4 (hKCa4)  Potassium intermediate/small conductance calcium-activated   12.78   6.05  
X00948  RLN2  Relaxin 2 (H2)   12.02   8.85  
M25753  CCNB1  CyclinB1   11.53   5.33  
W26466   NA   32f11   11.20   10.83  
X65233  ZNF80  Zinc finger protein 80 (pT17)   10.54   7.10  
U49089  DLG3  Discs, large (Drosophila) homolog 3   9.60   6.79  
AL080146  CCNB2  CyclinB2   9.56   7.18  
AI760162   NA   wg58e09.x1   9.19   4.34  
D87119  TRB2  Tribbles homolog 2   9.18   4.24  
AF030107  RGS13  Regulator of G-protein signaling 13   8.33   9.41  
AF024714  AIM2  Interferon-inducible protein (AIM2) absent in melanoma   8.26   5.74  
D13633  DLG7  Discs large homolog 7   7.53   3.06  
M37712  CDC2L2  Cell division cycle 2-like 2   7.16   7.26  
X01057  IL2RA  Interleukin 2 receptor, alpha*†  6.78   3.73  
AI375913   NA   tc14c08.x1   6.62   4.23  
AB020316  UST  Uronyl-2-sulfotransferase   6.58   3.72  
L25876  CDKN3  CIP2 (cyclin-dependent interacting protein 2) cyclin-dependent kinase inhibitor 3   6.39   8.06  
D38073  MCM3  Minichromosome maintenance deficient 3   6.34   2.71  
AB014566  DAAM1  Disheveled associated activator of morphogenesis 1   6.27   5.55  
AF007155  LOC254531  PISC domain containing hypothetical protein   6.14   4.20  
L47276  HUMTOPATR  Homo sapiens alpha topoisomerase truncated-form mRNA   6.12   4.03  
U37426  KIF11  Kinesin family member 11   6.12   3.15  
AB012911  FZD6  Frizzled homolog 6   6.12   5.48  
AL080121  DKFZp564O0823  Highly similar to rat castration induced prostatic apoptosis related protein-1   6.10   6.96  
X83490  TNFRSF6  Tumor necrosis factor receptor superfamily member 6* (Fas/APO-1)   6.02   3.85  
AL050107  TAZ  Transcriptional co-activator with PDZ (PSD-95, DLG, and ZO-1)—binding motif   5.81   5.67  
J04088  TOP2A  Topoisomerase (DNA) II alpha   5.59   4.52  
D42055  NEDD4  Neural precursor cell expressed, developmentally down-regulated 4   5.47   2.02  
D38251  POLR2E  Polymerase (RNA) II (DNA directed) polypeptide E   5.40   8.51  
M74089  LOC91137  Hypothetical protein BC017169   5.28   3.81  
D13643  DHCR24  24-dehydrocholesterol reductase   5.17   5.52  
D14657  KIAA0101  KIAA0101 gene product   4.94   3.93  
AA203476   NA   zx55e01.rl   4.92   2.31  
M13755  GIP2  Interferon, alpha-inducible protein   4.86   6.20  
U63743  KIF2C  Kinesin family member 2C   4.69   3.78  
J03473  ADPRT  ADP-ribosyltransferase   4.52   3.58  
U43916  EMP1  Epithelial membrane protein 1   4.49   2.75  
Z70519  TNFRSF6  FAS soluble protein*  4.44   2.69  
U73379  UBE2C  Ubiquitin-conjugating enzyme E2C   4.43   4.57  
D86062  C21orf33  Chromosome 21 open reading frame 33   4.41   7.29  
AI127424   NA   qb75b02.x1   4.36   6.10  
AC004528  C19orf6  Chromosome 19 open reading frame 6   4.31   4.16  
AL050069  DOK5  Docking protein 5   4.27   5.45  
U81561  PTPRN2  Protein tyrosine phosphatase, receptor type, N polypeptide 2   4.24   5.04  
M15205  TK1  Thymidine kinase 1, soluble   4.21   4.71  
M84443  GALK2  Galactokinase 2   4.09   2.29  
D63861  PPID  Peptidylprolyl isomerase D (cyclophilin D)   4.08   2.34  
X02883  HSTCRAC  Human gene for T-cell receptor alpha chain C region   4.05   2.81  
D00596  TYMS  Thymidylate synthetase   4.03   4.17  
U03494  TFCP2  Transcription factor CP2 (CCAAT protein)   3.99   3.15  
U31601  JAK3  Janus kinase 3 (a protein tyrosine kinase, leukocyte)   3.95   3.48  
AF009426  C18orf1  Chromosome 18 open reading frame 1   3.93   2.87  
AL022398  ADORA2BP  Adenosine A2b receptor pseudogene   3.90   2.80  
M97935  STAT1  Signal transducer and activator of transcription 1   3.89   4.36  
AA919102   NA   o184h02.sl   3.86   2.11  
U88964  ISG20  Interferon-stimulated gene   3.81   3.21  
AJ010953  ATP2CI  ATPase, Ca++ transporting, type 2C, member 1   3.73   2.87  
U53003  C21orf33  Chromosome 21 open reading frame 33   3.69   2.76  
M36711   NA   DNA-binding protein Ap-2   3.67   3.09  
M34641  FGFR1  Fibroblast growth factor receptor 1   3.62   2.37  
AI652660    wb30c10.x1   3.62   3.47  
AJ000534  SGCE  Sarcoglycan, epsilon   3.61   3.07  
D50920  THRAP4  Thyroid hormone receptor associated protein 4   3.48   2.05  
AB024704  TPX2  Microtubule-associated protein homolog   3.45   3.20  
X14798  ETS1  v-ets erythroblastosis virus E26 oncogene homolog 1   3.44   3.36  
Y11681  Y11681  Mitochondrial ribosomal protein S12   3.44   7.90  
D26155  SMARCA2  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2   3.42   3.10  
AL031737   NA   Human DNA sequence from clone 8B22 on chromosome 1p35.1-36.21   3.42   2.35  
M86699  TTK  TTK (threonine/tyrosine kinase) protein kinase   3.40   2.38  
U16799  ATP1B1  ATPase, Na+/K+ transporting, beta 1 polypeptide   3.39   3.81  
AB018270  MYO1D  Myosin ID   3.34   2.57  
U76638  BARD1  BRCA1 (breast cancer 1) associated RING domain 1   3.34   2.62  
AB013452  ATP8A1  ATPase, aminophospholipid transporter (APLT), class 1, type 8A, member 1   3.32   3.29  
Y11525  CEBPA  CCAAT/enhancer binding protein (C/EBP), alpha   3.32   3.34  
M34423  GLB1  Galactosidase, beta 1   3.31   4.04  
AA203213   NA   zx57e04.r1   3.31   3.49  
X64624  POU4F1  POU (Pit, Oct, Unc) domain, class 4, transcription factor 1   3.31   3.92  
AB018271  BPAG1  Bullous pemphigoid antigen 1   3.25   2.12  
LI3435   NA   Human chromosome 3p21.1 gene sequence   3.24   2.92  
AF055993  SAP30  Sin3-associated polypeptide   3.18   3.47  
U29332  FHL2  Four and a half LIM (Lin-1, Tsl-1, MEC-3) domains 2   3.16   3.60  
AI540958   NA   Homo sapiens cDNA, 5 end/clone_end=5   3.15   3.59  
D38522  SYT11  Synaptotagmin XI   3.09   3.58  
U01038  PLK1  Polo-like kinase 1   3.07   3.40  
X74262  RBBP4  Retinoblastoma binding protein 4   3.05   5.58  
L23959  TFDP1  Transcription factor Dp-1 (E2F dimerization partner-1)   3.03   3.76  
M87434  OAS2  2′-5′-oligoadenylate synthetase 2   3.02   2.96  
M25280  SELL  Selectin L (lymphocyte adhesion molecule 1)   3.02   3.31  
M63488  RPA1  Replication protein A1   3.01   3.39  
U78190  GCHFR  GTP cyclohydrolase I feedback regulatory protein   3.01   2.09  
AF067656  ZWINT  ZW10 interactor   2.97   2.50  
M15024  MYB  v-myb myeloblastosis viral oncogene homolog   2.97   4.54  
M81830  SSTR2  Somatostatin receptor 2   2.96   3.33  
D28364  ANXA11  Annexin II, 5   2.96   6.05  
M63838  FI16  Interferon, gamma-inducible protein 16   2.92   3.05  
X72889   NA   NA   2.91   2.45  
AC003108  Anxa6  Annexin VI   2.84   3.79  
L07541  RFC3  Replication factor C (activator 1) 3   2.83   2.67  
D78261  IRF4  Interferon regulatory factor 4*  2.83   3.14  
AA005018   NA   zh96a09.rl   2.83   2.12  
AA310786   NA   EST181572 Homo sapiens cDNA   2.78   2.29  
M87284  OAS2  2′-5′-oligoadenylate synthetase 2   2.77   3.11  
U09813  ATP5G3  ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9) isoform 3   2.76   4.85  
AC005253  UBA52  Ubiquitin A-52 residue ribosomal protein fusion product 1   2.75   2.85  
AF070523  JWA  Cytoskeleton related vitamin A responsive protein   2.75   2.29  
U38545  PLD1  Phospholipase D1, phophatidylcholine-specific   2.74   2.17  
U25182  PRDX4  Peroxiredoxin 4   2.73   3.10  
AF022385  PDCD10  Programmed cell death 10   2.73   2.09  
AF000416  EXTL2  Exostoses (multiple)-like 2   2.73   2.13  
D26361  KIF14  Kinesin family member 14   2.72   2.47  
AF064084  ICMT  Isoprenylcysteine carboxyl methyltransferase   2.70   4.31  
X98248  SORT1  Sortilin 1   2.69   5.01  
U65410  MAD2L1  MAD2 (mitotic arrest-deficient 2) mitotic arrest deficient-like 1   2.66   2.73  
U51004  HINT1  Histidine triad nucleotide binding protein 1   2.64   2.09  
M23379  RASA1  RAS p21 protein activator (GTPase activating protein) 1   2.64   2.43  
X57398  PM5  pM5 protein   2.63   2.65  
X65550  MK167  Antigen identified by monoclonal antibody Ki-67   2.60   3.41  
J05614  PCNA  Proliferating cell nuclear antigen†  2.59   2.50  
X67951  PRDX1  Peroxiredoxin 1   2.58   2.16  
M11507  TFRC  Transferrin receptor (p90, CD71)   2.57   2.59  
D26599  PSMB2  Proteasome (prosome, macropain) subunit, beta type, 2   2.55   2.91  
AF053551  MTX2  Metaxin 2   2.53   3.54  
AF016898  BATF  Basic leucine zipper transcription factor, AT-like   2.50   2.04  
AF055993  SAP30  sin3-associated polypeptide   2.49   2.73  
D14710  ATP5A1  ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit, isoform 1   2.48   2.01  
U09564   NA   Human serine kinase   2.48   2.51  
AL109672  P24B  Integral type I protein   2.48   3.85  
AI056696   NA   oz26h05.x1   2.44   2.65  
M13228  MYCN  v-myc myelocytomatosis viral related oncogene, neuroblastoma derived   2.44   2.78  
AI566877   NA   tn24f02.x1   2.44   2.25  
L09235  ATP6V1A  ATPase, H+ transporting, lysosomal   2.42   5.18  
X51688  CCNA2  Cyclin A2   2.36   2.45  
U13695  PMS1  Postmeiotic segregation increased 1   2.34   2.17  
AB007455  TP53AP1  TP53 activated protein 1   2.33   2.77  
D44497  CORO1A  Coronin, actin binding protein, 1A   2.33   2.77  
AA255502   NA   zr85b06.r1   2.33   2.78  
X73066  NME1  Non-metastatic cells 1, protein (NM23A) expressed in   2.32   3.00  
AI347088   NA   qp60d09.x1   2.32   2.21  
U37689  POLR2H  Polymerase (RNA) II (DNA directed) polypeptide H   2.32   2.13  
U86529  GSTZ1  Glutathione transferase zeta 1   2.32   2.28  
J03133  SP1  SP1 (SV40 promoter 1) transcription factor   2.31   4.73  
AB007447  FLN29  FLN29 gene product (TNF receptor factor-like protein)   2.30   2.34  
X74008  PPP1CC  Protein phosphatase 1, catalytic subunit, gamma isoform   2.30   2.07  
U56833  VBP1  von Hippel-Lindau binding protein 1   2.29   2.16  
AF020038  IDH1  Isocitrate dehydrogenase 1 (NADP+), soluble   2.29   3.40  
U63809  PAWR  PRKC (protein kinase C), apoptosis, WT1, regulator   2.29   2.35  
AL050034  ADPRTL3  ADP-ribosyltransferase-like 3   2.25   2.09  
M87339  HUMACT1A  Human replication factor C, 37-kDa subunit   2.25   2.98  
AA056747   NA   zk81f02.s1   2.24   2.95  
U10886  PTPRJ  Protein tyrosine phosphatase, receptor type, J   2.23   2.52  
X84194  ACYP1  A-cylphosphatase 1, erythrocyte (common) type   2.23   4.40  
AB024401  ING1  Inhibitor of growth family, member 1   2.20   14.85  
M19481  FST  Follistatin   2.20   2.54  
AF006084  ARPC1B  Actin related protein 2/3 complex, subunit 1B,   2.19   3.71  
Y00097  ANXA6  Annexin A6   2.19   2.00  
D00017  ANXA2  Annexin A2   2.18   2.81  
U50079  HDAC1  Histone deacetylase 1   2.17   2.62  
AA811338   NA   ob81g05.sl   2.17   5.19  
M97676  MSX1  msh homeo box homolog 1   2.16   3.15  
M63573  PPIB  Peptidylprolyl isomerase B (cyclophilin B)   2.16   2.85  
J00314  OK/SW-cl.56  beta 5-tubulin   2.16   2.19  
U30872  CENPF  Centromere protein F   2.16   2.43  
AA969267   NA   on57d12.sl   2.13   2.49  
AF053306  BUB1B  Budding uninhibited by benzimidazoles 1 homolog beta   2.13   2.04  
AF042384  BC-2  Putative breast adenocarcinoma marker   2.12   2.52  
U32849  NMI  N-myc (and STAT) interactor   2.12   2.90  
AB028975  KIAA1052  KIAA1052 protein   2.12   2.53  
AJ000480  C8FW  Phosphoprotein regulated by mitogenic pathways   2.11   4.49  
D50692  MYCBP  c-myc binding protein   2.10   3.00  
M16279  CD99  CD99 antigen   2.10   2.94  
X69398  CD47  CD47 antigen (Rh-related antigen)   2.09   2.17  
AF054825  VAMP5  Vesicle-associated membrane protein 5   2.09   2.69  
D37984  RECQL  RecQ protein-like (DNA helicase Q1-like)   2.09   2.27  
U90549  HMGN4  High mobility group nucleosomal binding domain 4   2.09   2.16  
AF087036  MSC  Musculin (activated B-cell factor-1)   2.08   2.67  
J04058  ETFA  Electron-transfer-flavoprotein, alpha polypeptide   2.06   2.54  
X62534  HMGB2  High-mobility group box 2   2.04   2.26  
S57501   NA   Protein phosphatase 1, alpha catalytic subunit   2.04   2.71  
AJ001612  PSPHL  Phosphoserine phosphatase-like   2.03   2.89  
AJ245416  LSM2  LSM2 (Sm-like protein 2) homolog, U6 small nuclear RNA associated   2.03   2.18  
U91932  AP3S1  Adaptor-related protein complex 3, sigma 1 subunit   2.03   2.89  
U74612  FOXM1  Forkhead box M1   2.02   2.17  
L42243
 		IFNAR2
 		 Interferon (alpha, beta, and omega) receptor 2
 		 2.02
 		 2.88
 
Fold change
Accession no.
Symbol
Gene
CD4+
CD45RO+
AF070648  CAV1  Caveolin 1*  34.82   49.74  
AF150241  PGDS  Prostaglandin D2 synthase   31.21   12.56  
AL080181  TSLC1  Tumor suppressor in lung cancer 1   30.36   36.86  
M36711  TFAP2A  Transcription factor AP-2 alpha   19.14   11.28  
AF079529  PDE8B  Phosphodiesterase 8B   17.58   13.07  
AB002305  ARNT2  Aryl-hydrocarbon receptor nuclear translocator 2   17.15   22.59  
X58288  PTPRM  Protein tyrosine phosphatase, receptor type, M   15.89   5.12  
Y00664  NMYC  V-myc myelocytomatosis viral related oncogene, neuroblastoma   15.30   12.11  
J03802  PTHLH  Parathyroid hormone-like hormone*†  14.10   8.68  
AF022797  KCNN4 (hKCa4)  Potassium intermediate/small conductance calcium-activated   12.78   6.05  
X00948  RLN2  Relaxin 2 (H2)   12.02   8.85  
M25753  CCNB1  CyclinB1   11.53   5.33  
W26466   NA   32f11   11.20   10.83  
X65233  ZNF80  Zinc finger protein 80 (pT17)   10.54   7.10  
U49089  DLG3  Discs, large (Drosophila) homolog 3   9.60   6.79  
AL080146  CCNB2  CyclinB2   9.56   7.18  
AI760162   NA   wg58e09.x1   9.19   4.34  
D87119  TRB2  Tribbles homolog 2   9.18   4.24  
AF030107  RGS13  Regulator of G-protein signaling 13   8.33   9.41  
AF024714  AIM2  Interferon-inducible protein (AIM2) absent in melanoma   8.26   5.74  
D13633  DLG7  Discs large homolog 7   7.53   3.06  
M37712  CDC2L2  Cell division cycle 2-like 2   7.16   7.26  
X01057  IL2RA  Interleukin 2 receptor, alpha*†  6.78   3.73  
AI375913   NA   tc14c08.x1   6.62   4.23  
AB020316  UST  Uronyl-2-sulfotransferase   6.58   3.72  
L25876  CDKN3  CIP2 (cyclin-dependent interacting protein 2) cyclin-dependent kinase inhibitor 3   6.39   8.06  
D38073  MCM3  Minichromosome maintenance deficient 3   6.34   2.71  
AB014566  DAAM1  Disheveled associated activator of morphogenesis 1   6.27   5.55  
AF007155  LOC254531  PISC domain containing hypothetical protein   6.14   4.20  
L47276  HUMTOPATR  Homo sapiens alpha topoisomerase truncated-form mRNA   6.12   4.03  
U37426  KIF11  Kinesin family member 11   6.12   3.15  
AB012911  FZD6  Frizzled homolog 6   6.12   5.48  
AL080121  DKFZp564O0823  Highly similar to rat castration induced prostatic apoptosis related protein-1   6.10   6.96  
X83490  TNFRSF6  Tumor necrosis factor receptor superfamily member 6* (Fas/APO-1)   6.02   3.85  
AL050107  TAZ  Transcriptional co-activator with PDZ (PSD-95, DLG, and ZO-1)—binding motif   5.81   5.67  
J04088  TOP2A  Topoisomerase (DNA) II alpha   5.59   4.52  
D42055  NEDD4  Neural precursor cell expressed, developmentally down-regulated 4   5.47   2.02  
D38251  POLR2E  Polymerase (RNA) II (DNA directed) polypeptide E   5.40   8.51  
M74089  LOC91137  Hypothetical protein BC017169   5.28   3.81  
D13643  DHCR24  24-dehydrocholesterol reductase   5.17   5.52  
D14657  KIAA0101  KIAA0101 gene product   4.94   3.93  
AA203476   NA   zx55e01.rl   4.92   2.31  
M13755  GIP2  Interferon, alpha-inducible protein   4.86   6.20  
U63743  KIF2C  Kinesin family member 2C   4.69   3.78  
J03473  ADPRT  ADP-ribosyltransferase   4.52   3.58  
U43916  EMP1  Epithelial membrane protein 1   4.49   2.75  
Z70519  TNFRSF6  FAS soluble protein*  4.44   2.69  
U73379  UBE2C  Ubiquitin-conjugating enzyme E2C   4.43   4.57  
D86062  C21orf33  Chromosome 21 open reading frame 33   4.41   7.29  
AI127424   NA   qb75b02.x1   4.36   6.10  
AC004528  C19orf6  Chromosome 19 open reading frame 6   4.31   4.16  
AL050069  DOK5  Docking protein 5   4.27   5.45  
U81561  PTPRN2  Protein tyrosine phosphatase, receptor type, N polypeptide 2   4.24   5.04  
M15205  TK1  Thymidine kinase 1, soluble   4.21   4.71  
M84443  GALK2  Galactokinase 2   4.09   2.29  
D63861  PPID  Peptidylprolyl isomerase D (cyclophilin D)   4.08   2.34  
X02883  HSTCRAC  Human gene for T-cell receptor alpha chain C region   4.05   2.81  
D00596  TYMS  Thymidylate synthetase   4.03   4.17  
U03494  TFCP2  Transcription factor CP2 (CCAAT protein)   3.99   3.15  
U31601  JAK3  Janus kinase 3 (a protein tyrosine kinase, leukocyte)   3.95   3.48  
AF009426  C18orf1  Chromosome 18 open reading frame 1   3.93   2.87  
AL022398  ADORA2BP  Adenosine A2b receptor pseudogene   3.90   2.80  
M97935  STAT1  Signal transducer and activator of transcription 1   3.89   4.36  
AA919102   NA   o184h02.sl   3.86   2.11  
U88964  ISG20  Interferon-stimulated gene   3.81   3.21  
AJ010953  ATP2CI  ATPase, Ca++ transporting, type 2C, member 1   3.73   2.87  
U53003  C21orf33  Chromosome 21 open reading frame 33   3.69   2.76  
M36711   NA   DNA-binding protein Ap-2   3.67   3.09  
M34641  FGFR1  Fibroblast growth factor receptor 1   3.62   2.37  
AI652660    wb30c10.x1   3.62   3.47  
AJ000534  SGCE  Sarcoglycan, epsilon   3.61   3.07  
D50920  THRAP4  Thyroid hormone receptor associated protein 4   3.48   2.05  
AB024704  TPX2  Microtubule-associated protein homolog   3.45   3.20  
X14798  ETS1  v-ets erythroblastosis virus E26 oncogene homolog 1   3.44   3.36  
Y11681  Y11681  Mitochondrial ribosomal protein S12   3.44   7.90  
D26155  SMARCA2  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2   3.42   3.10  
AL031737   NA   Human DNA sequence from clone 8B22 on chromosome 1p35.1-36.21   3.42   2.35  
M86699  TTK  TTK (threonine/tyrosine kinase) protein kinase   3.40   2.38  
U16799  ATP1B1  ATPase, Na+/K+ transporting, beta 1 polypeptide   3.39   3.81  
AB018270  MYO1D  Myosin ID   3.34   2.57  
U76638  BARD1  BRCA1 (breast cancer 1) associated RING domain 1   3.34   2.62  
AB013452  ATP8A1  ATPase, aminophospholipid transporter (APLT), class 1, type 8A, member 1   3.32   3.29  
Y11525  CEBPA  CCAAT/enhancer binding protein (C/EBP), alpha   3.32   3.34  
M34423  GLB1  Galactosidase, beta 1   3.31   4.04  
AA203213   NA   zx57e04.r1   3.31   3.49  
X64624  POU4F1  POU (Pit, Oct, Unc) domain, class 4, transcription factor 1   3.31   3.92  
AB018271  BPAG1  Bullous pemphigoid antigen 1   3.25   2.12  
LI3435   NA   Human chromosome 3p21.1 gene sequence   3.24   2.92  
AF055993  SAP30  Sin3-associated polypeptide   3.18   3.47  
U29332  FHL2  Four and a half LIM (Lin-1, Tsl-1, MEC-3) domains 2   3.16   3.60  
AI540958   NA   Homo sapiens cDNA, 5 end/clone_end=5   3.15   3.59  
D38522  SYT11  Synaptotagmin XI   3.09   3.58  
U01038  PLK1  Polo-like kinase 1   3.07   3.40  
X74262  RBBP4  Retinoblastoma binding protein 4   3.05   5.58  
L23959  TFDP1  Transcription factor Dp-1 (E2F dimerization partner-1)   3.03   3.76  
M87434  OAS2  2′-5′-oligoadenylate synthetase 2   3.02   2.96  
M25280  SELL  Selectin L (lymphocyte adhesion molecule 1)   3.02   3.31  
M63488  RPA1  Replication protein A1   3.01   3.39  
U78190  GCHFR  GTP cyclohydrolase I feedback regulatory protein   3.01   2.09  
AF067656  ZWINT  ZW10 interactor   2.97   2.50  
M15024  MYB  v-myb myeloblastosis viral oncogene homolog   2.97   4.54  
M81830  SSTR2  Somatostatin receptor 2   2.96   3.33  
D28364  ANXA11  Annexin II, 5   2.96   6.05  
M63838  FI16  Interferon, gamma-inducible protein 16   2.92   3.05  
X72889   NA   NA   2.91   2.45  
AC003108  Anxa6  Annexin VI   2.84   3.79  
L07541  RFC3  Replication factor C (activator 1) 3   2.83   2.67  
D78261  IRF4  Interferon regulatory factor 4*  2.83   3.14  
AA005018   NA   zh96a09.rl   2.83   2.12  
AA310786   NA   EST181572 Homo sapiens cDNA   2.78   2.29  
M87284  OAS2  2′-5′-oligoadenylate synthetase 2   2.77   3.11  
U09813  ATP5G3  ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9) isoform 3   2.76   4.85  
AC005253  UBA52  Ubiquitin A-52 residue ribosomal protein fusion product 1   2.75   2.85  
AF070523  JWA  Cytoskeleton related vitamin A responsive protein   2.75   2.29  
U38545  PLD1  Phospholipase D1, phophatidylcholine-specific   2.74   2.17  
U25182  PRDX4  Peroxiredoxin 4   2.73   3.10  
AF022385  PDCD10  Programmed cell death 10   2.73   2.09  
AF000416  EXTL2  Exostoses (multiple)-like 2   2.73   2.13  
D26361  KIF14  Kinesin family member 14   2.72   2.47  
AF064084  ICMT  Isoprenylcysteine carboxyl methyltransferase   2.70   4.31  
X98248  SORT1  Sortilin 1   2.69   5.01  
U65410  MAD2L1  MAD2 (mitotic arrest-deficient 2) mitotic arrest deficient-like 1   2.66   2.73  
U51004  HINT1  Histidine triad nucleotide binding protein 1   2.64   2.09  
M23379  RASA1  RAS p21 protein activator (GTPase activating protein) 1   2.64   2.43  
X57398  PM5  pM5 protein   2.63   2.65  
X65550  MK167  Antigen identified by monoclonal antibody Ki-67   2.60   3.41  
J05614  PCNA  Proliferating cell nuclear antigen†  2.59   2.50  
X67951  PRDX1  Peroxiredoxin 1   2.58   2.16  
M11507  TFRC  Transferrin receptor (p90, CD71)   2.57   2.59  
D26599  PSMB2  Proteasome (prosome, macropain) subunit, beta type, 2   2.55   2.91  
AF053551  MTX2  Metaxin 2   2.53   3.54  
AF016898  BATF  Basic leucine zipper transcription factor, AT-like   2.50   2.04  
AF055993  SAP30  sin3-associated polypeptide   2.49   2.73  
D14710  ATP5A1  ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit, isoform 1   2.48   2.01  
U09564   NA   Human serine kinase   2.48   2.51  
AL109672  P24B  Integral type I protein   2.48   3.85  
AI056696   NA   oz26h05.x1   2.44   2.65  
M13228  MYCN  v-myc myelocytomatosis viral related oncogene, neuroblastoma derived   2.44   2.78  
AI566877   NA   tn24f02.x1   2.44   2.25  
L09235  ATP6V1A  ATPase, H+ transporting, lysosomal   2.42   5.18  
X51688  CCNA2  Cyclin A2   2.36   2.45  
U13695  PMS1  Postmeiotic segregation increased 1   2.34   2.17  
AB007455  TP53AP1  TP53 activated protein 1   2.33   2.77  
D44497  CORO1A  Coronin, actin binding protein, 1A   2.33   2.77  
AA255502   NA   zr85b06.r1   2.33   2.78  
X73066  NME1  Non-metastatic cells 1, protein (NM23A) expressed in   2.32   3.00  
AI347088   NA   qp60d09.x1   2.32   2.21  
U37689  POLR2H  Polymerase (RNA) II (DNA directed) polypeptide H   2.32   2.13  
U86529  GSTZ1  Glutathione transferase zeta 1   2.32   2.28  
J03133  SP1  SP1 (SV40 promoter 1) transcription factor   2.31   4.73  
AB007447  FLN29  FLN29 gene product (TNF receptor factor-like protein)   2.30   2.34  
X74008  PPP1CC  Protein phosphatase 1, catalytic subunit, gamma isoform   2.30   2.07  
U56833  VBP1  von Hippel-Lindau binding protein 1   2.29   2.16  
AF020038  IDH1  Isocitrate dehydrogenase 1 (NADP+), soluble   2.29   3.40  
U63809  PAWR  PRKC (protein kinase C), apoptosis, WT1, regulator   2.29   2.35  
AL050034  ADPRTL3  ADP-ribosyltransferase-like 3   2.25   2.09  
M87339  HUMACT1A  Human replication factor C, 37-kDa subunit   2.25   2.98  
AA056747   NA   zk81f02.s1   2.24   2.95  
U10886  PTPRJ  Protein tyrosine phosphatase, receptor type, J   2.23   2.52  
X84194  ACYP1  A-cylphosphatase 1, erythrocyte (common) type   2.23   4.40  
AB024401  ING1  Inhibitor of growth family, member 1   2.20   14.85  
M19481  FST  Follistatin   2.20   2.54  
AF006084  ARPC1B  Actin related protein 2/3 complex, subunit 1B,   2.19   3.71  
Y00097  ANXA6  Annexin A6   2.19   2.00  
D00017  ANXA2  Annexin A2   2.18   2.81  
U50079  HDAC1  Histone deacetylase 1   2.17   2.62  
AA811338   NA   ob81g05.sl   2.17   5.19  
M97676  MSX1  msh homeo box homolog 1   2.16   3.15  
M63573  PPIB  Peptidylprolyl isomerase B (cyclophilin B)   2.16   2.85  
J00314  OK/SW-cl.56  beta 5-tubulin   2.16   2.19  
U30872  CENPF  Centromere protein F   2.16   2.43  
AA969267   NA   on57d12.sl   2.13   2.49  
AF053306  BUB1B  Budding uninhibited by benzimidazoles 1 homolog beta   2.13   2.04  
AF042384  BC-2  Putative breast adenocarcinoma marker   2.12   2.52  
U32849  NMI  N-myc (and STAT) interactor   2.12   2.90  
AB028975  KIAA1052  KIAA1052 protein   2.12   2.53  
AJ000480  C8FW  Phosphoprotein regulated by mitogenic pathways   2.11   4.49  
D50692  MYCBP  c-myc binding protein   2.10   3.00  
M16279  CD99  CD99 antigen   2.10   2.94  
X69398  CD47  CD47 antigen (Rh-related antigen)   2.09   2.17  
AF054825  VAMP5  Vesicle-associated membrane protein 5   2.09   2.69  
D37984  RECQL  RecQ protein-like (DNA helicase Q1-like)   2.09   2.27  
U90549  HMGN4  High mobility group nucleosomal binding domain 4   2.09   2.16  
AF087036  MSC  Musculin (activated B-cell factor-1)   2.08   2.67  
J04058  ETFA  Electron-transfer-flavoprotein, alpha polypeptide   2.06   2.54  
X62534  HMGB2  High-mobility group box 2   2.04   2.26  
S57501   NA   Protein phosphatase 1, alpha catalytic subunit   2.04   2.71  
AJ001612  PSPHL  Phosphoserine phosphatase-like   2.03   2.89  
AJ245416  LSM2  LSM2 (Sm-like protein 2) homolog, U6 small nuclear RNA associated   2.03   2.18  
U91932  AP3S1  Adaptor-related protein complex 3, sigma 1 subunit   2.03   2.89  
U74612  FOXM1  Forkhead box M1   2.02   2.17  
L42243
 		IFNAR2
 		 Interferon (alpha, beta, and omega) receptor 2
 		 2.02
 		 2.88
 

Listed genes were selected by expression rate greater than 100 and more than 2-fold expression in ATL cells more than in CD4+ and CD4+CD45RO+ T cells with significant differences (P < .01). For all genes scored, the fold change was calculated by the mean expression value of ATL cells by those of CD4+ or CD4+CD45RO+ T cells. NA indicates not applicable.

*

Genes were already reported as genes with high expression in HTLV-1—infected T cells.

†

Genes were already reported as genes with high expression in ATL cells.

View Large
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal