Genetic characteristics of anticoagulated patients
Polymorphism . | Allele . | N (%) . | Genotype . | N (%) . |
|---|---|---|---|---|
| VKORC1 | ||||
| 1173C>T | C | 177 (60.2) | CC | 54 (36.8) |
| T | 117 (39.8) | CT | 69 (46.9) | |
| TT | 24 (16.3) | |||
| 3730G>A | G | 192 (65.3) | GG | 67 (45.5) |
| A | 102 (34.7) | GA | 58 (39.5) | |
| AA | 22 (15.0) | |||
| CYP2C9 | ||||
| Arg144Cys | Arg | 244 (83.0) | Arg/Arg | 97 (66.0) |
| Cys | 50 (17.0) | Arg/Cys | 50 (34.0) | |
| Cys/Cys | — | |||
| Ile359Leu | Ile | 268 (91.2) | Ile/Ile | 122 (83.0) |
| Leu | 26 (8.8) | Leu/Ile | 24 (16.3) | |
| Leu/Leu | 1 (0.7) |
Polymorphism . | Allele . | N (%) . | Genotype . | N (%) . |
|---|---|---|---|---|
| VKORC1 | ||||
| 1173C>T | C | 177 (60.2) | CC | 54 (36.8) |
| T | 117 (39.8) | CT | 69 (46.9) | |
| TT | 24 (16.3) | |||
| 3730G>A | G | 192 (65.3) | GG | 67 (45.5) |
| A | 102 (34.7) | GA | 58 (39.5) | |
| AA | 22 (15.0) | |||
| CYP2C9 | ||||
| Arg144Cys | Arg | 244 (83.0) | Arg/Arg | 97 (66.0) |
| Cys | 50 (17.0) | Arg/Cys | 50 (34.0) | |
| Cys/Cys | — | |||
| Ile359Leu | Ile | 268 (91.2) | Ile/Ile | 122 (83.0) |
| Leu | 26 (8.8) | Leu/Ile | 24 (16.3) | |
| Leu/Leu | 1 (0.7) |
- indicates —.