Characteristics of the 32 patients studied
. | Phase 1 . | Phase 2 . |
|---|---|---|
| No. | 12 | 20 |
| Diagnosis, no. | ||
| AML | 9 | 16 |
| MDS | 1 | 3 |
| ALL | 2 | 0 |
| CML | 0 | 1 |
| Age, y, median (range) | 56 (23-74) | 63 (18-84) |
| Cytogenetics, no. | ||
| Diploid | 6 | 7 |
| -5/-7 | 1 | 4 |
| Other | 5 | 9 |
| Disease status, no. | ||
| First relapse | 11 | 13 |
| Primary refractory | 1 | 6 |
| CRD1, mo, median (range) | 7.6 (0-17.1) | 5.2 (0-18) |
. | Phase 1 . | Phase 2 . |
|---|---|---|
| No. | 12 | 20 |
| Diagnosis, no. | ||
| AML | 9 | 16 |
| MDS | 1 | 3 |
| ALL | 2 | 0 |
| CML | 0 | 1 |
| Age, y, median (range) | 56 (23-74) | 63 (18-84) |
| Cytogenetics, no. | ||
| Diploid | 6 | 7 |
| -5/-7 | 1 | 4 |
| Other | 5 | 9 |
| Disease status, no. | ||
| First relapse | 11 | 13 |
| Primary refractory | 1 | 6 |
| CRD1, mo, median (range) | 7.6 (0-17.1) | 5.2 (0-18) |
CRD1 indicates duration of first complete remission; AML, acute myeloid leukemia; MDS, myelodsyplastic syndrome; ALL, acute lymphoblastic leukemia; CML, chronic myeloid leukemia; -5/-7, monosomy of chromosomes 5 and 7.