Table 3.

Summary of the 2-trait locus results


Pair of chromosomes

Two-locus penetrance matrix

Disease allele frequencies, P

Two-locus LOD score

Position on first chromosome

Position on second chromosome
9 and 11   0.0002 0.0002 0.0002 0.9000   Chr 9: .0001   3.15   42.73 (directly at D9S171)   98.51 (directly at D11S2000)  
  0.0002 0.0002 0.0002 0.9000   Chr 11: .0001     
  0.0002 0.0002 0.0002 0.9000      
  0.7000 0.7000 0.7000 0.9700      
5 and 11   0.0000 0.0000 0.1000 0.1000   Chr 5: .03   4.44   78.31 (directly at D5S2003)   92.07 (directly at D11S4176)  
  0.0000 0.0000 0.1000 0.1000   Chr 11: .05     
  0.0000 0.0000 0.8000 0.8000      

 
0.0000 0.0000 0.8000 0.8000
 

 

 

 

 

Pair of chromosomes

Two-locus penetrance matrix

Disease allele frequencies, P

Two-locus LOD score

Position on first chromosome

Position on second chromosome
9 and 11   0.0002 0.0002 0.0002 0.9000   Chr 9: .0001   3.15   42.73 (directly at D9S171)   98.51 (directly at D11S2000)  
  0.0002 0.0002 0.0002 0.9000   Chr 11: .0001     
  0.0002 0.0002 0.0002 0.9000      
  0.7000 0.7000 0.7000 0.9700      
5 and 11   0.0000 0.0000 0.1000 0.1000   Chr 5: .03   4.44   78.31 (directly at D5S2003)   92.07 (directly at D11S4176)  
  0.0000 0.0000 0.1000 0.1000   Chr 11: .05     
  0.0000 0.0000 0.8000 0.8000      

 
0.0000 0.0000 0.8000 0.8000
 

 

 

 

 

The row of the penetrance matrix reflects the genotype at the first trait locus; the column reflects the genotype at the second trait locus, in the order f+/+, fm/+, f+/m, fm/m. Chr indicates chromosome.

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