Toxicity*
. | Grade 1/2 . | Grade 3 . | Grade 4/5 . |
|---|---|---|---|
| Nausea/vomiting | 13 | - | - |
| Anorexia | 5 | - | - |
| Diarrhea | 5 | - | - |
| Edema | 9 | - | - |
| Fatigue | 7 | 1 | - |
| Headache | 7 | - | - |
| Fever | 8 | - | - |
| Hyperbilirubinemia | - | 1 | - |
| Pleural effusion | - | 1 | - |
| Hypoxia | - | 2 | - |
| Tachycardia | - | 1 | - |
| Transaminitis | - | 1 | - |
| Cardiac troponin | - | - | 1 (grade 4) |
| Pulmonary | - | - | 3 (grade 5) |
. | Grade 1/2 . | Grade 3 . | Grade 4/5 . |
|---|---|---|---|
| Nausea/vomiting | 13 | - | - |
| Anorexia | 5 | - | - |
| Diarrhea | 5 | - | - |
| Edema | 9 | - | - |
| Fatigue | 7 | 1 | - |
| Headache | 7 | - | - |
| Fever | 8 | - | - |
| Hyperbilirubinemia | - | 1 | - |
| Pleural effusion | - | 1 | - |
| Hypoxia | - | 2 | - |
| Tachycardia | - | 1 | - |
| Transaminitis | - | 1 | - |
| Cardiac troponin | - | - | 1 (grade 4) |
| Pulmonary | - | - | 3 (grade 5) |
- indicates no instances noted (except for single occurrences of grade 1/2 toxicities).
Grade 1 or 2 toxicities occurring in 2 or more patients and all grade 3 to 5 toxicities.