Table 3.

Base-line APACHE II scores and baseline markers of protein C activation and inhibition in survivors and in nonsurvivors



Survivors (n = 14)

Nonsurvivors (n = 18)

Variable
Mean (SD)
Min, max
Mean (SD)
Min, max
2-sided P
APACHE II   19.8 (6.8)   8, 37   21.7 (6.9)   10, 34   .41  
PC (U/mL)   0.52 (0.23)   0.15, 0.97   0.44 (0.23)   0.16, 0.96   .20  
F1 + 2 (nM)   1.6 (0.6)   0.9, 2.6   2.2 (1.2)   1.1, 5.8   .18  
APC (ng/mL)   5.27 (2.24)   1.54, 9.21   3.66 (1.64)   0.71, 6.47   .024  
F1 + 2-to-APC ratio
 
0.57 (0.31)
 
0.20, 1.20
 
1.11 (0.80)
 
0.30, 2.90
 
.047
 


Survivors (n = 14)

Nonsurvivors (n = 18)

Variable
Mean (SD)
Min, max
Mean (SD)
Min, max
2-sided P
APACHE II   19.8 (6.8)   8, 37   21.7 (6.9)   10, 34   .41  
PC (U/mL)   0.52 (0.23)   0.15, 0.97   0.44 (0.23)   0.16, 0.96   .20  
F1 + 2 (nM)   1.6 (0.6)   0.9, 2.6   2.2 (1.2)   1.1, 5.8   .18  
APC (ng/mL)   5.27 (2.24)   1.54, 9.21   3.66 (1.64)   0.71, 6.47   .024  
F1 + 2-to-APC ratio
 
0.57 (0.31)
 
0.20, 1.20
 
1.11 (0.80)
 
0.30, 2.90
 
.047
 

Baseline APACHE II scores and baseline markers of endogenous protein C activation for survivors and nonsurvivors were compared using the Wilcoxon rank sum test. Data are summarized using means, standard deviations (SD), minimums (min), and maximums (max).

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