Table 2.

Base-line markers of protein C activation and inhibition



Severe sepsis (n = 32)

Healthy volunteers (n = 11)
Variable
Mean (SD)
Min, max
Mean (SD)
Min, max
Protein C (U/mL)   0.48 (0.23)   0.15, 0.97   0.86 (0.16)   0.64, 1.12  
F1 + 2 (nM)   1.99 (1.00)   0.77, 5.81   0.84 (0.19)   0.56, 1.16  
TAT (μg/L)   12.6 (11.1)   3.9, 42.6   2.6 (0.7)   2.0, 4.2  
APC (ng/mL)   4.36 (2.06)   0.71, 9.21   1.18 (0.64)   <0.25, 1.76  
α1-AT (U/mL)
 
1.10 (0.21)
 
0.76, 1.30
 
1.0 (0.21)
 
0.70, 1.38
 


Severe sepsis (n = 32)

Healthy volunteers (n = 11)
Variable
Mean (SD)
Min, max
Mean (SD)
Min, max
Protein C (U/mL)   0.48 (0.23)   0.15, 0.97   0.86 (0.16)   0.64, 1.12  
F1 + 2 (nM)   1.99 (1.00)   0.77, 5.81   0.84 (0.19)   0.56, 1.16  
TAT (μg/L)   12.6 (11.1)   3.9, 42.6   2.6 (0.7)   2.0, 4.2  
APC (ng/mL)   4.36 (2.06)   0.71, 9.21   1.18 (0.64)   <0.25, 1.76  
α1-AT (U/mL)
 
1.10 (0.21)
 
0.76, 1.30
 
1.0 (0.21)
 
0.70, 1.38
 

Data are summarized using means, standard deviations (SD), minimums (min), and maximums (max).

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