Colony formation from sorted BM mononuclear cells of Fli-1+/– chimeric mice
. | No. colonies, mean ± SD . | . | . | . | . | . | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Cell type plated . | G . | M . | GM . | E . | Mixed . | Total . | |||||
| Experiment 1 | |||||||||||
| Ly-5.2 | 28 ± 6 | 87 ± 6* | 6 ± 1 | 11 ± 4† | 1 ± 1 | 133 ± 8† | |||||
| Ly-5.1 | 15 ± 1 | 48 ± 3 | 10 ± 4 | 1 ± 2 | 0 ± 1 | 74 ± 3 | |||||
| Experiment 2 | |||||||||||
| Ly-5.2 | 24 ± 4* | 73 ± 7* | 5 ± 2 | 11 ± 4† | 1 ± 0 | 113 ± 13† | |||||
| Ly-5.1 | 13 ± 3 | 35 ± 4 | 5 ± 2 | 1 ± 1 | 1 ± 1 | 55 ± 7 | |||||
| Experiment 3 | |||||||||||
| Ly-5.2 | 26 ± 7 | 103 ± 14† | 13 ± 4† | 6 ± 2* | 5 ± 2 | 152 ± 17† | |||||
| Ly-5.1 | 20 ± 4 | 77 ± 6 | 6 ± 3 | 1 ± 2 | 3 ± 1 | 107 ± 12 | |||||
. | No. colonies, mean ± SD . | . | . | . | . | . | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Cell type plated . | G . | M . | GM . | E . | Mixed . | Total . | |||||
| Experiment 1 | |||||||||||
| Ly-5.2 | 28 ± 6 | 87 ± 6* | 6 ± 1 | 11 ± 4† | 1 ± 1 | 133 ± 8† | |||||
| Ly-5.1 | 15 ± 1 | 48 ± 3 | 10 ± 4 | 1 ± 2 | 0 ± 1 | 74 ± 3 | |||||
| Experiment 2 | |||||||||||
| Ly-5.2 | 24 ± 4* | 73 ± 7* | 5 ± 2 | 11 ± 4† | 1 ± 0 | 113 ± 13† | |||||
| Ly-5.1 | 13 ± 3 | 35 ± 4 | 5 ± 2 | 1 ± 1 | 1 ± 1 | 55 ± 7 | |||||
| Experiment 3 | |||||||||||
| Ly-5.2 | 26 ± 7 | 103 ± 14† | 13 ± 4† | 6 ± 2* | 5 ± 2 | 152 ± 17† | |||||
| Ly-5.1 | 20 ± 4 | 77 ± 6 | 6 ± 3 | 1 ± 2 | 3 ± 1 | 107 ± 12 | |||||
Numbers represent mean ± SD of colonies from 4000 BM MNCs in quadruplicate culture.
P values were determined for differences between Ly-5.2 and Ly-5.1 groups.
G indicates granulocyte colonies; M, macrophage colonies; GM, granulocyte-macrophage colonies; E, erythroid bursts; mixed, granulocyte-macrophage-erythrocyte colonies.
P < .01.
P < .05.