Comparison of lineage expression by Ly-5.2 and Ly-5.1 cell populations of Fli-1+/– and Fli-1-/- chimeric mice
. | Fli-1+/- . | . | Fli-1-/- . | . | ||
|---|---|---|---|---|---|---|
| Tissue and lineage . | Ly-5.2 . | Ly-5.1 . | Ly-5.2 . | Ly-5.1 . | ||
| PB | ||||||
| Gr1brightMac1+, % | 4.1 ± 1.9* | 10.8 ± 3.6 | 1.1, 1.6 (1.4) | 12.2,16.1 (14.2) | ||
| Gr1dim/-Mac1+, % | 10.9 ± 2.8† | 15.8 ± 1.9 | 12.5, 8.3 (10.4) | 14.9,16.1 (15.5) | ||
| B220+, % | 44.9 ± 1.1‡ | 35.2 ± 6.7 | 30.4,26.2 (28.3) | 46.5,40.2 (43.4) | ||
| CD4+, % | 20.1 ± 4.6 | 20.5 ± 3.0 | 24.4,35.6 (30.0) | 14.4,13.6 (14.0) | ||
| CD8+, % | 14.4 ± 3.2 | 14.4 ± 2.3 | 19.9,18.3 (19.1) | 11.2, 9.4 (10.3) | ||
| NK1.1+, % | 4.8 ± 1.1‡ | 3.7 ± 0.6 | 5.4, 4.9 (5.2) | 2.6, 2.2 (2.4) | ||
| BM | ||||||
| Gr1brightMac1+, % | 36.6 ± 2.2 | 43.2 ± 8.5 | 22.1 | 54.7 | ||
| Gr1dim/-Mac1+, % | 22.3 ± 1.8 | 23.0 ± 2.4 | 18.5 | 23.8 | ||
| B220+, % | 30.1 ± 2.5 | 22.3 ± 9.2 | 27.0 | 11.0 | ||
| CD4+, % | 5.1 ± 0.3‡ | 2.3 ± 0.5 | 6.8 | 1.5 | ||
| CD8+, % | 2.8 ± 0.9‡ | 1.7 ± 0.8 | 5.2 | 1.1 | ||
| NK1,1+, % | 3.8 ± 0.2† | 1.8 ± 0.2 | 7.7 | 2.0 | ||
. | Fli-1+/- . | . | Fli-1-/- . | . | ||
|---|---|---|---|---|---|---|
| Tissue and lineage . | Ly-5.2 . | Ly-5.1 . | Ly-5.2 . | Ly-5.1 . | ||
| PB | ||||||
| Gr1brightMac1+, % | 4.1 ± 1.9* | 10.8 ± 3.6 | 1.1, 1.6 (1.4) | 12.2,16.1 (14.2) | ||
| Gr1dim/-Mac1+, % | 10.9 ± 2.8† | 15.8 ± 1.9 | 12.5, 8.3 (10.4) | 14.9,16.1 (15.5) | ||
| B220+, % | 44.9 ± 1.1‡ | 35.2 ± 6.7 | 30.4,26.2 (28.3) | 46.5,40.2 (43.4) | ||
| CD4+, % | 20.1 ± 4.6 | 20.5 ± 3.0 | 24.4,35.6 (30.0) | 14.4,13.6 (14.0) | ||
| CD8+, % | 14.4 ± 3.2 | 14.4 ± 2.3 | 19.9,18.3 (19.1) | 11.2, 9.4 (10.3) | ||
| NK1.1+, % | 4.8 ± 1.1‡ | 3.7 ± 0.6 | 5.4, 4.9 (5.2) | 2.6, 2.2 (2.4) | ||
| BM | ||||||
| Gr1brightMac1+, % | 36.6 ± 2.2 | 43.2 ± 8.5 | 22.1 | 54.7 | ||
| Gr1dim/-Mac1+, % | 22.3 ± 1.8 | 23.0 ± 2.4 | 18.5 | 23.8 | ||
| B220+, % | 30.1 ± 2.5 | 22.3 ± 9.2 | 27.0 | 11.0 | ||
| CD4+, % | 5.1 ± 0.3‡ | 2.3 ± 0.5 | 6.8 | 1.5 | ||
| CD8+, % | 2.8 ± 0.9‡ | 1.7 ± 0.8 | 5.2 | 1.1 | ||
| NK1,1+, % | 3.8 ± 0.2† | 1.8 ± 0.2 | 7.7 | 2.0 | ||
Data for Fli-1+/- chimeric mice represent mean ± SD (n = 7 for PB; n = 4 for BM) of percentage of lineage-positive cells within Ly-5.2 or Ly-5.1 cell population. The mean of the percentage of lineage-positive cells of 2 Fli-1-/- chimeric mice appear in parentheses. BM from only one Fli-1-/- mouse was analyzed.
P values were determined for differences between Ly-5.2 and Ly-5.1 groups.
P < .001.
P < .01.
P < .05.