Demographic and clinical characteristics of patients according to treatment assignment
. | CALGB 9712 . | CALGB 9011 . | P . |
|---|---|---|---|
| No. of patients | 104 | 178 | |
| Median age, y (range) | 63 (38-88) | 64 (37-87) | .75 |
| Patients younger than 50 y, % | 14 | 14 | .93 |
| Patients aged 70 y or older, % | 23 | 25 | .88 |
| Rai stage I, % | 2 | 2 | |
| Rai stage II, % | 57 | 55 | |
| Rai stage III, % | 14 | 41 | < .0001 |
| Rai stage IV, % | 26 | 2 | |
| Enlarged liver, % | 15 | 20 | .43 |
| Enlarged spleen, % | 61 | 68 | .19 |
| Median WBC, 109/L (range) | 83 (9-436) | 77 (9-709) | .39 |
| Median Hgb, g/dL (range) | 12.3 (1.3-16.1) | 12.0 (4.6-16.6) | .26 |
| Median platelets, × 109/L (range) | 158 (33-316) | 155 (12-451) | .57 |
| Median, LDH, IU (range) | 212 (92-950) | 198 (39-1389) | .20 |
. | CALGB 9712 . | CALGB 9011 . | P . |
|---|---|---|---|
| No. of patients | 104 | 178 | |
| Median age, y (range) | 63 (38-88) | 64 (37-87) | .75 |
| Patients younger than 50 y, % | 14 | 14 | .93 |
| Patients aged 70 y or older, % | 23 | 25 | .88 |
| Rai stage I, % | 2 | 2 | |
| Rai stage II, % | 57 | 55 | |
| Rai stage III, % | 14 | 41 | < .0001 |
| Rai stage IV, % | 26 | 2 | |
| Enlarged liver, % | 15 | 20 | .43 |
| Enlarged spleen, % | 61 | 68 | .19 |
| Median WBC, 109/L (range) | 83 (9-436) | 77 (9-709) | .39 |
| Median Hgb, g/dL (range) | 12.3 (1.3-16.1) | 12.0 (4.6-16.6) | .26 |
| Median platelets, × 109/L (range) | 158 (33-316) | 155 (12-451) | .57 |
| Median, LDH, IU (range) | 212 (92-950) | 198 (39-1389) | .20 |
Hgb indicates hemoglobin.