Antibody staining intensity on melanoma-reactive CD8+ T cells (MFI)
. | . | . | Time relative to cell transfer . | . | . | ||
|---|---|---|---|---|---|---|---|
| Marker, patient . | Before . | TIL . | 1 wk . | 1 mo . | 2 mo or longer . | ||
| CD27 | |||||||
| 9 | ND | 5 | 4 | 5 | 8 | ||
| 10 | 62 | 12 | 6 | 18 | 45 | ||
| 20 | 108 | 30 | 25 | 67 | 49 | ||
| 21 | 424 | 5 | 7 | 17 | 11 | ||
| 23 | 351 | 9 | 7 | 38 | 20 | ||
| 28 | 43 | 10 | 9 | 60 | 41 | ||
| CD28 | |||||||
| 9 | ND | 12 | 93 | 113 | 119 | ||
| 10 | 34 | 7 | 6 | 8 | 21 | ||
| 20 | 55 | 17 | 31 | 41 | 62 | ||
| 21 | 124 | 33 | 254 | 263 | 65 | ||
| 23 | 169 | 8 | 275 | 64 | 7 | ||
| 28 | 21 | 3 | 18 | 24 | 77 | ||
| IL-7Rα | |||||||
| 9 | ND | 3 | 59 | 80 | 100 | ||
| 10 | 75 | 9 | 48 | 66 | 100 | ||
| 20 | 20 | 7 | 16 | 38 | 24 | ||
| 21 | 291 | 12 | 247 | 372 | 69 | ||
| 23 | 15 | 25 | 206 | 246 | 35 | ||
| 28 | 35 | 3 | 10 | 9 | 85 | ||
. | . | . | Time relative to cell transfer . | . | . | ||
|---|---|---|---|---|---|---|---|
| Marker, patient . | Before . | TIL . | 1 wk . | 1 mo . | 2 mo or longer . | ||
| CD27 | |||||||
| 9 | ND | 5 | 4 | 5 | 8 | ||
| 10 | 62 | 12 | 6 | 18 | 45 | ||
| 20 | 108 | 30 | 25 | 67 | 49 | ||
| 21 | 424 | 5 | 7 | 17 | 11 | ||
| 23 | 351 | 9 | 7 | 38 | 20 | ||
| 28 | 43 | 10 | 9 | 60 | 41 | ||
| CD28 | |||||||
| 9 | ND | 12 | 93 | 113 | 119 | ||
| 10 | 34 | 7 | 6 | 8 | 21 | ||
| 20 | 55 | 17 | 31 | 41 | 62 | ||
| 21 | 124 | 33 | 254 | 263 | 65 | ||
| 23 | 169 | 8 | 275 | 64 | 7 | ||
| 28 | 21 | 3 | 18 | 24 | 77 | ||
| IL-7Rα | |||||||
| 9 | ND | 3 | 59 | 80 | 100 | ||
| 10 | 75 | 9 | 48 | 66 | 100 | ||
| 20 | 20 | 7 | 16 | 38 | 24 | ||
| 21 | 291 | 12 | 247 | 372 | 69 | ||
| 23 | 15 | 25 | 206 | 246 | 35 | ||
| 28 | 35 | 3 | 10 | 9 | 85 | ||