CI values for the apoptotic effects of daunorubicin and SU11248 on FLT3 ITD–positive cell lines
. | ED50 . | ED75 . | ED90 . |
|---|---|---|---|
| MV4-11 | 1.00 | 0.67 | 0.49 |
| MOLM14 | 0.98 | 0.57 | 0.34 |
| BAF3 ITD FLT3 | 0.96 | 0.72 | 0.55 |
. | ED50 . | ED75 . | ED90 . |
|---|---|---|---|
| MV4-11 | 1.00 | 0.67 | 0.49 |
| MOLM14 | 0.98 | 0.57 | 0.34 |
| BAF3 ITD FLT3 | 0.96 | 0.72 | 0.55 |
The experimental CI values are less than 1 for all given dose effects, with the lowest CI values (indicating the greatest degree of synergy) seen when ED90 was used as the experimental end point.