CI values for the effects of SU11248 and cytarabine on cellular proliferation
. | ED50 . | ED75 . | ED90 . |
|---|---|---|---|
| MV4-11 | 0.93 | 0.86 | 0.82 |
| MOLM14 | 1.00 | 0.86 | 0.85 |
| BAF3 ITD FLT3 | 1.35 | 1.09 | 0.91 |
| BAF3 WT FLT3 + FL | 0.71 | 0.74 | 0.76 |
| BAF3 D835V FLT3 | 0.59 | 0.71 | 0.87 |
. | ED50 . | ED75 . | ED90 . |
|---|---|---|---|
| MV4-11 | 0.93 | 0.86 | 0.82 |
| MOLM14 | 1.00 | 0.86 | 0.85 |
| BAF3 ITD FLT3 | 1.35 | 1.09 | 0.91 |
| BAF3 WT FLT3 + FL | 0.71 | 0.74 | 0.76 |
| BAF3 D835V FLT3 | 0.59 | 0.71 | 0.87 |
CI values significantly less than 1 indicate synergy; values close to 1, an additive effect and values significantly greater than 1, an antagonistic effect of the 2 agents.