Table 3.

Thymic dyslymphopoiesis in 6-week-old APEX2-null mice



Cell count, × 105 in thymus*
Types of cells
Wild type
APEX2-null
Total cells   1156 ± 125   234 ± 32  
CD4CD8  45 ± 7   25 ± 5  
CD4+CD8+  982 ± 128   179 ± 24  
CD4CD8+  33 ± 3   10 ± 3  
CD4+CD8  96 ± 8   20 ± 3  
CD3+
 
88 ± 14
 
18 ± 3
 


Cell count, × 105 in thymus*
Types of cells
Wild type
APEX2-null
Total cells   1156 ± 125   234 ± 32  
CD4CD8  45 ± 7   25 ± 5  
CD4+CD8+  982 ± 128   179 ± 24  
CD4CD8+  33 ± 3   10 ± 3  
CD4+CD8  96 ± 8   20 ± 3  
CD3+
 
88 ± 14
 
18 ± 3
 
*

The mean ± standard deviation representing 5 mice.

P < .01 by Welch t test.

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