Table 2. Moderate dyshematopoiesis in 6-... | American Society of Hematology

Table 2.

Moderate dyshematopoiesis in 6- and 13-week-old APEX2-null mice

	Density, counts/μL^*
Age of mice and cell type	Wild type	APEX2-null
6 wks
WBC†	5400 ± 1095	2275 ± 640
RBC, × 10⁴‡	928 ± 41	771 ± 29
PLT, × 10⁴	60 ± 17	73 ± 25
CD11b⁺/D×5⁻‡	877 ± 338	482 ± 154
D×5⁺/CD3⁻	522 ± 151	391 ± 90
B220⁺†	3064 ± 513	1021 ± 308
CD3⁺†	1440 ± 344	643 ± 179
CD8⁺ CD3⁺†	506 ± 109	227 ± 59
CD4⁺ CD3⁺†	817 ± 150	345 ± 86
13 wks
WBC†	6800 ± 748	3640 ± 804
RBC, × 10⁴†	945 ± 42	833 ± 29
PLT, × 10⁴	85 ± 24	105 ± 19

	Density, counts/μL^*
Age of mice and cell type	Wild type	APEX2-null
6 wks
WBC†	5400 ± 1095	2275 ± 640
RBC, × 10⁴‡	928 ± 41	771 ± 29
PLT, × 10⁴	60 ± 17	73 ± 25
CD11b⁺/D×5⁻‡	877 ± 338	482 ± 154
D×5⁺/CD3⁻	522 ± 151	391 ± 90
B220⁺†	3064 ± 513	1021 ± 308
CD3⁺†	1440 ± 344	643 ± 179
CD8⁺ CD3⁺†	506 ± 109	227 ± 59
CD4⁺ CD3⁺†	817 ± 150	345 ± 86
13 wks
WBC†	6800 ± 748	3640 ± 804
RBC, × 10⁴†	945 ± 42	833 ± 29
PLT, × 10⁴	85 ± 24	105 ± 19

WBC indicates white blood cells; RBC, red blood cells; PLT, platelets,

The mean ± standard deviation representing at least 5 mice.

P < .01 by Welch t test.

P < .05 by Welch t test.