Table 3.

Comparison of Mn2+-and DTT-induced fibrinogen binding to αIIbβ3 measured using laser tweezers


Conditions

Average yield strength, pN

Cumulative probability, %
Ca2+  82 ± 15   2.1 ± 0.6  
Mn2+  88 ± 14   4.5 ± 0.8  
No DTT, Ca2+  89 ± 9   1.9 ± 0.5  
DTT, Ca2+
 
88 ± 9
 
3.2 ± 0.6
 

Conditions

Average yield strength, pN

Cumulative probability, %
Ca2+  82 ± 15   2.1 ± 0.6  
Mn2+  88 ± 14   4.5 ± 0.8  
No DTT, Ca2+  89 ± 9   1.9 ± 0.5  
DTT, Ca2+
 
88 ± 9
 
3.2 ± 0.6
 
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