Table 2. Molecular dimensions of... | American Society of Hematology

Table 2.

Molecular dimensions of individual αIIbβ3 molecules in the presence of Ca²⁺ or Mn²⁺

		Head
	No. of images measured	Transverse length, nm^*	Vertical length, nm^*	Stalk separation, nm^*
Ca²⁺
Closed	123	11.2 ± 1.5	8.0 ± 1.5	—
Open	97	12.1 ± 1.8	8.0 ± 1.6	13.7 ± 4.1
+ Fibrinogen	66	—	—	12.6 ± 2.7
Mn²⁺
Closed	95	10.9 ± 1.5	7.3 ± 1.5	—
Open	95	12.6 ± 1.5†	8.4 ± 1.1‡	17.8 ± 3.6
+ Fibrinogen	71	—	—	19.9 ± 4.7§

		Head
	No. of images measured	Transverse length, nm^*	Vertical length, nm^*	Stalk separation, nm^*
Ca²⁺
Closed	123	11.2 ± 1.5	8.0 ± 1.5	—
Open	97	12.1 ± 1.8	8.0 ± 1.6	13.7 ± 4.1
+ Fibrinogen	66	—	—	12.6 ± 2.7
Mn²⁺
Closed	95	10.9 ± 1.5	7.3 ± 1.5	—
Open	95	12.6 ± 1.5†	8.4 ± 1.1‡	17.8 ± 3.6
+ Fibrinogen	71	—	—	19.9 ± 4.7§

— indicates unmeasurable parameters.

Data are given as mean ± 1 SD.

Mn²⁺/open versus Mn²⁺/closed, P < 10⁻⁸.

Mn²⁺/open versus Mn²⁺/closed, P < 10⁻⁴.

Mn²⁺/fibrinogen versus Mn²⁺/open, P = 10⁻³.