Description of study subjects
. | . | . | . | t-AML study . | . | . | ||
|---|---|---|---|---|---|---|---|---|
| . | . | Leukaemia Research Fund study . | . | . | Previous therapy . | . | ||
| Variable . | AML 11 . | Controls . | De novo AML . | All cases . | Radiotherapy only . | Chemotherapy* . | ||
| No. | 341 | 729 | 420 | 91 | 40 | 51 | ||
| Sex | ||||||||
| Male, no. (%) | 143 (42) | 393 (54) | 227 (54) | 36 (40) | 11 (28) | 25 (49) | ||
| Female, no. (%) | 198 (58) | 336 (46) | 193 (46) | 55 (60) | 29 (73) | 26 (51) | ||
| Age, y | ||||||||
| Mean (standard deviation) | 66.9 (5.5) | 48.1 (14.3) | 47.5 (14.5) | 55.3 (13.6) | 61.0 (8.5) | 50.8 (14.8) | ||
| Median | 66.6 | 50.3 | 49.9 | 58.7 | 62.1 | 52.7 | ||
| Age groups | ||||||||
| 16 to 39 y, no. (%) | 0 | 218 (30) | 132 (31) | 16 (18) | 0 | 16 (31) | ||
| 40 to 59 y, no. (%) | 38 (11) | 322 (44) | 180 (43) | 34 (37) | 17 (43) | 17 (33) | ||
| 60 to 69 y, no. (%) | 206 (60) | 189 (26) | 108 (26) | 41 (45) | 23 (58) | 18 (35) | ||
| 70 to 74 y, no. (%) | 72 (21) | 0 | 0 | 0 | 0 | 0 | ||
| 75 y or more, no. (%) | 25 (7) | 0 | 0 | 0 | 0 | 0 | ||
. | . | . | . | t-AML study . | . | . | ||
|---|---|---|---|---|---|---|---|---|
| . | . | Leukaemia Research Fund study . | . | . | Previous therapy . | . | ||
| Variable . | AML 11 . | Controls . | De novo AML . | All cases . | Radiotherapy only . | Chemotherapy* . | ||
| No. | 341 | 729 | 420 | 91 | 40 | 51 | ||
| Sex | ||||||||
| Male, no. (%) | 143 (42) | 393 (54) | 227 (54) | 36 (40) | 11 (28) | 25 (49) | ||
| Female, no. (%) | 198 (58) | 336 (46) | 193 (46) | 55 (60) | 29 (73) | 26 (51) | ||
| Age, y | ||||||||
| Mean (standard deviation) | 66.9 (5.5) | 48.1 (14.3) | 47.5 (14.5) | 55.3 (13.6) | 61.0 (8.5) | 50.8 (14.8) | ||
| Median | 66.6 | 50.3 | 49.9 | 58.7 | 62.1 | 52.7 | ||
| Age groups | ||||||||
| 16 to 39 y, no. (%) | 0 | 218 (30) | 132 (31) | 16 (18) | 0 | 16 (31) | ||
| 40 to 59 y, no. (%) | 38 (11) | 322 (44) | 180 (43) | 34 (37) | 17 (43) | 17 (33) | ||
| 60 to 69 y, no. (%) | 206 (60) | 189 (26) | 108 (26) | 41 (45) | 23 (58) | 18 (35) | ||
| 70 to 74 y, no. (%) | 72 (21) | 0 | 0 | 0 | 0 | 0 | ||
| 75 y or more, no. (%) | 25 (7) | 0 | 0 | 0 | 0 | 0 | ||
Nineteen patients also received radiotherapy.