Incidence of grades 2 to 4 nonhematologic toxicities during remission induction therapy with intensive chemotherapy and imatinib
Adverse event . | Grade 2, no. (%) . | Grade 3, no. (%) . | Grade 4, no. (%) . |
---|---|---|---|
Sepsis | 0 | 3 (13) | 0 |
Other febrile neutropenia | 1 (4) | 6 (26) | 0 |
Symptomatic CMV infection | 0 | 2 (8) | 0 |
Lung hemorrhage | 1 (4) | 0 | 1 (4) |
Diarrhea | 1 (4) | 1 (4) | 0 |
Ileus | 1 (4) | 2 (8) | 0 |
Nausea | 1 (4) | 4 (17) | 0 |
GPT | 4 (17) | 3 (13) | 0 |
Jaundice | 1 (4) | 0 | 0 |
Pancreatitis | 0 | 1 (4) | 0 |
Hyperglycemia | 2 (8) | 1 (4) | 0 |
Hypophosphatemia | 1 (4) | 0 | 0 |
Hypokalemia | 0 | 1 (4) | 0 |
Fluid retention | 1 (4) | 0 | 0 |
Depression | 3 (13) | 0 | 0 |
Muscle weakness | 0 | 1 (4) | 0 |
Adverse event . | Grade 2, no. (%) . | Grade 3, no. (%) . | Grade 4, no. (%) . |
---|---|---|---|
Sepsis | 0 | 3 (13) | 0 |
Other febrile neutropenia | 1 (4) | 6 (26) | 0 |
Symptomatic CMV infection | 0 | 2 (8) | 0 |
Lung hemorrhage | 1 (4) | 0 | 1 (4) |
Diarrhea | 1 (4) | 1 (4) | 0 |
Ileus | 1 (4) | 2 (8) | 0 |
Nausea | 1 (4) | 4 (17) | 0 |
GPT | 4 (17) | 3 (13) | 0 |
Jaundice | 1 (4) | 0 | 0 |
Pancreatitis | 0 | 1 (4) | 0 |
Hyperglycemia | 2 (8) | 1 (4) | 0 |
Hypophosphatemia | 1 (4) | 0 | 0 |
Hypokalemia | 0 | 1 (4) | 0 |
Fluid retention | 1 (4) | 0 | 0 |
Depression | 3 (13) | 0 | 0 |
Muscle weakness | 0 | 1 (4) | 0 |
CMV indicates cytomegalovirus.