Table 3.

Functional classification of the specific genes


Description

GenBank accession no.

Quantitative RT-PCR SLR
De novo-expressed genes in ET MKs   
    Enzymes    
        Phospholipase A2, group IVC (cytosolic, calcium-independent)  AF065214.1   2.9  
    Receptors    
        CD14 antigen NM_000591.1  4.1  
        Gamma-aminobutyric acid (GABA) B receptor, 1 NM_001470.1  2.7  
        Tyrosine kinase with immunoglobulin and epidermal growth factor homology domains NM_005424.1  2.2  
    Transcription regulators    
        Chromodomain helicase DNA binding protein 3  BE379542   1.8  
    Others    
        Seven in absentia homolog 1 (Drosophila)  U70056   NA  
        Splicing factor, arginine/serine-rich 2, interacting protein  AI984932   NA  
        Tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory)  NM_000362.2  NA  
        KIAA0285 gene product  R61539   NA  
        KIAA0542 gene product  AB011114.2   NA  
Absent genes in ET MKs present in normal counterparts   
    Enzymes    
        Tryptase beta 1  AF206665.1   NA  
        Tryptase beta 2 NM_024164.2  NA  
    Transcription factors    
        HIF-1 responsive RTP801 NM_019058.1  -2.7  
    Creatin transporters    
        Solute carrier family 6 (neurotransmitter transporter, creatine), member 8 NM_005629.1  -2.5  
    Others    
        Rag D protein  AF272036.1   NA  
        Tubulin beta-5  BC002654.1   NA  
        Centaurin, beta 1 NM_014716.1  NA  
        ESTs, Weakly similar to N-WASP (H sapiens)  BF968134   NA  
        Consensus includes AF099143/DEF = Homo sapiens mast cell tryptase beta III gene, complete cds
 
AF099143
 
NA
 

Description

GenBank accession no.

Quantitative RT-PCR SLR
De novo-expressed genes in ET MKs   
    Enzymes    
        Phospholipase A2, group IVC (cytosolic, calcium-independent)  AF065214.1   2.9  
    Receptors    
        CD14 antigen NM_000591.1  4.1  
        Gamma-aminobutyric acid (GABA) B receptor, 1 NM_001470.1  2.7  
        Tyrosine kinase with immunoglobulin and epidermal growth factor homology domains NM_005424.1  2.2  
    Transcription regulators    
        Chromodomain helicase DNA binding protein 3  BE379542   1.8  
    Others    
        Seven in absentia homolog 1 (Drosophila)  U70056   NA  
        Splicing factor, arginine/serine-rich 2, interacting protein  AI984932   NA  
        Tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory)  NM_000362.2  NA  
        KIAA0285 gene product  R61539   NA  
        KIAA0542 gene product  AB011114.2   NA  
Absent genes in ET MKs present in normal counterparts   
    Enzymes    
        Tryptase beta 1  AF206665.1   NA  
        Tryptase beta 2 NM_024164.2  NA  
    Transcription factors    
        HIF-1 responsive RTP801 NM_019058.1  -2.7  
    Creatin transporters    
        Solute carrier family 6 (neurotransmitter transporter, creatine), member 8 NM_005629.1  -2.5  
    Others    
        Rag D protein  AF272036.1   NA  
        Tubulin beta-5  BC002654.1   NA  
        Centaurin, beta 1 NM_014716.1  NA  
        ESTs, Weakly similar to N-WASP (H sapiens)  BF968134   NA  
        Consensus includes AF099143/DEF = Homo sapiens mast cell tryptase beta III gene, complete cds
 
AF099143
 
NA
 

NA indicates not applicable.

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