Table 4. Multivariable model of... | American Society of Hematology

Table 4.

Multivariable model of nonrelapse mortality*

Variable	Hazard ratio†(95% CI)	P‡
Prednisone dose per mg/kg	2.6 (2.0-3.4)	< .0001
Platelet count less than 100 000/μL at diagnosis	2.2 (1.5-3.1)	< .0001
Acute GVHD, versus 0-I		.002
Grade II	0.9 (0.5-1.6)
Grades III-IV	1.7 (0.9-3.1)
Serum bilirubin level more than 2 mg/dL at diagnosis	2.1 (1.4-2.9)	.0002
Donor age per 10 y	1.2 (1.0-1.4)	.009
No. of HLA-mismatched loci per locus	1.3 (1.1-1.5)	.01
Patient age per 10 y	1.2 (1.1-1.4)	.002

Variable	Hazard ratio†(95% CI)	P‡
Prednisone dose per mg/kg	2.6 (2.0-3.4)	< .0001
Platelet count less than 100 000/μL at diagnosis	2.2 (1.5-3.1)	< .0001
Acute GVHD, versus 0-I		.002
Grade II	0.9 (0.5-1.6)
Grades III-IV	1.7 (0.9-3.1)
Serum bilirubin level more than 2 mg/dL at diagnosis	2.1 (1.4-2.9)	.0002
Donor age per 10 y	1.2 (1.0-1.4)	.009
No. of HLA-mismatched loci per locus	1.3 (1.1-1.5)	.01
Patient age per 10 y	1.2 (1.1-1.4)	.002

Twelve patients were excluded from this model because of missing data.

In this model, recurrent malignancy was treated as a competing risk. Follow-up was censored for patients who had recurrent malignancy before death.

Likelihood ratio test.