Table 2.

Patient characteristics at initial diagnosis of chronic GVHD


Characteristic



No. unknown
Months from transplantation to diagnosis, median (range)   3.9 (2.2-28.2)   0  
Type of onset, no. (%)   45  
    De novo   103 (15)   
    Quiescent   501 (71)   
    Progressive   102 (14)   
Sites involved, no. (%)   
    Skin   566 (75)   1  
    Eyes   185 (25)   9  
    Mouth   378 (51)   5  
    Liver   249 (33)   0  
    Gastrointestinal tract   340 (45)   2  
    Other*  47 (6)   1  
No. of sites involved (%)   0  
    1-2   432 (58)   
    3   246 (33)   
    More than 3   73 (10)   
Dose of prednisone at diagnosis, mg/kg, no. (%)   0  
    None   280 (37)   
    More than 0 but less than 0.5   220 (29)   
    0.5-1.0   155 (21)   
    More than 1.0   96 (13)   
Platelet count less than 100 000/μL at diagnosis, no. (%)   343 (46)   2  
Serum bilirubin level more than 2 mg/dL at diagnosis, no. (%)
 
121 (16)
 
5
 

Characteristic



No. unknown
Months from transplantation to diagnosis, median (range)   3.9 (2.2-28.2)   0  
Type of onset, no. (%)   45  
    De novo   103 (15)   
    Quiescent   501 (71)   
    Progressive   102 (14)   
Sites involved, no. (%)   
    Skin   566 (75)   1  
    Eyes   185 (25)   9  
    Mouth   378 (51)   5  
    Liver   249 (33)   0  
    Gastrointestinal tract   340 (45)   2  
    Other*  47 (6)   1  
No. of sites involved (%)   0  
    1-2   432 (58)   
    3   246 (33)   
    More than 3   73 (10)   
Dose of prednisone at diagnosis, mg/kg, no. (%)   0  
    None   280 (37)   
    More than 0 but less than 0.5   220 (29)   
    0.5-1.0   155 (21)   
    More than 1.0   96 (13)   
Platelet count less than 100 000/μL at diagnosis, no. (%)   343 (46)   2  
Serum bilirubin level more than 2 mg/dL at diagnosis, no. (%)
 
121 (16)
 
5
 
*

Lung (n = 27), female genital tract (n = 8), and muscle or fascia (n = 6) were the most frequently affected sites.

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