Response rates for FCM and R-FCM for patients with follicular lymphomas and mantle cell lymphomas
. | Follicular lymphoma (FL) . | . | Mantle cell lymphoma (MCL) . | . | ||
|---|---|---|---|---|---|---|
. | FCM . | R-FCM . | FCM . | R-FCM . | ||
| No. of evaluable patients | 30 | 35 | 24 | 24 | ||
| CR, % | 23 | 40 | 0 | 29 | ||
| PR, % | 47 | 54 | 46 | 29 | ||
| MR, % | 7 | 0 | 0 | 4 | ||
| SD, % | 7 | 0 | 0 | 8 | ||
| PD, % | 17 | 3 | 42 | 29 | ||
| EX, % | 0 | 3 | 13 | 0 | ||
| PR + CR, % | 70 | 94 | 46 | 58 | ||
. | Follicular lymphoma (FL) . | . | Mantle cell lymphoma (MCL) . | . | ||
|---|---|---|---|---|---|---|
. | FCM . | R-FCM . | FCM . | R-FCM . | ||
| No. of evaluable patients | 30 | 35 | 24 | 24 | ||
| CR, % | 23 | 40 | 0 | 29 | ||
| PR, % | 47 | 54 | 46 | 29 | ||
| MR, % | 7 | 0 | 0 | 4 | ||
| SD, % | 7 | 0 | 0 | 8 | ||
| PD, % | 17 | 3 | 42 | 29 | ||
| EX, % | 0 | 3 | 13 | 0 | ||
| PR + CR, % | 70 | 94 | 46 | 58 | ||
R-FCM was superior to FCM in both lymphoma subtypes. In FL the overall response rate (CR and PR) was 94% versus 70% (P = .011); in MCL it was 58% versus 46% (P = .282).
CR indicates complete remission; PR, partial remission; MR, minor response; SD, stable disease; PD, progressive disease; and EX, death.