Table 9.

Complications of hemophilia treatment




1972

1978

1985

1992

2001
Inhibitory antibodies*      
    Cumulative incidence, proportion of patients     31/384   51/388   52/420  
    Current inhibitors, no. of patients (%)   —   —   19 (5)   29 (7)   15 (4)  
    Past inhibitors, no. of patients (%)   —   —   12 (3)   22 (6)   37 (9)  
HIV infection, no. of patients (%)  —   —   36 (4)   55 (8)   29 (5)  
Hepatitis C, no. of patients (%)      
    Current infection   —   —   —   —   344 (45)  
    Past infection
 

 

 

 

 
97 (13)
 



1972

1978

1985

1992

2001
Inhibitory antibodies*      
    Cumulative incidence, proportion of patients     31/384   51/388   52/420  
    Current inhibitors, no. of patients (%)   —   —   19 (5)   29 (7)   15 (4)  
    Past inhibitors, no. of patients (%)   —   —   12 (3)   22 (6)   37 (9)  
HIV infection, no. of patients (%)  —   —   36 (4)   55 (8)   29 (5)  
Hepatitis C, no. of patients (%)      
    Current infection   —   —   —   —   344 (45)  
    Past infection
 

 

 

 

 
97 (13)
 

—indicates no data available.

*

Reported for patients with severe hemophilia.

Reported for patients treated with clotting factor before 1985.

Reported for patients treated with clotting factor before 1992.

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