Cox regression analysis of prognostic factors for survival from diagnosis
. | Univariate . | . | . | Multivariate . | . | . | ||||
|---|---|---|---|---|---|---|---|---|---|---|
. | HR . | 95% CI . | P . | HR . | 95% CI . | P . | ||||
| AF1q expression, high versus low | 2.41 | 1.19-4.88 | .015 | 3.05 | 1.31-7.09 | .009 | ||||
| Timing, standard versus intensive | 1.24 | 1.02-1.49 | .03 | 0.88 | 0.39-1.98 | .758 | ||||
| WBC, at least 100 versus fewer than 100, mm3 | 1.29 | 1.02-1.62 | .033 | 1.41 | 0.60-3.35 | .430 | ||||
| Race, nonwhite versus white | 1.30 | 1.07-1.59 | .008 | 0.94 | 0.41-2.19 | .893 | ||||
| ras gene, activated versus wild type | 2.04 | 1.15-3.63 | .015 | 1.76 | 0.67-4.65 | .254 | ||||
| FLT3/ITD, positive versus negative | 1.78 | 0.89-3.54 | .101 | 1.13 | 0.39-3.30 | .820 | ||||
| FAB, M1 versus other FAB | 1.24 | 0.51-3.03 | .636 | 0.74 | 0.27-2.03 | .557 | ||||
| Cytogenetics, high-risk versus other | 1.53 | 0.91-2.59 | .111 | — | — | — | ||||
. | Univariate . | . | . | Multivariate . | . | . | ||||
|---|---|---|---|---|---|---|---|---|---|---|
. | HR . | 95% CI . | P . | HR . | 95% CI . | P . | ||||
| AF1q expression, high versus low | 2.41 | 1.19-4.88 | .015 | 3.05 | 1.31-7.09 | .009 | ||||
| Timing, standard versus intensive | 1.24 | 1.02-1.49 | .03 | 0.88 | 0.39-1.98 | .758 | ||||
| WBC, at least 100 versus fewer than 100, mm3 | 1.29 | 1.02-1.62 | .033 | 1.41 | 0.60-3.35 | .430 | ||||
| Race, nonwhite versus white | 1.30 | 1.07-1.59 | .008 | 0.94 | 0.41-2.19 | .893 | ||||
| ras gene, activated versus wild type | 2.04 | 1.15-3.63 | .015 | 1.76 | 0.67-4.65 | .254 | ||||
| FLT3/ITD, positive versus negative | 1.78 | 0.89-3.54 | .101 | 1.13 | 0.39-3.30 | .820 | ||||
| FAB, M1 versus other FAB | 1.24 | 0.51-3.03 | .636 | 0.74 | 0.27-2.03 | .557 | ||||
| Cytogenetics, high-risk versus other | 1.53 | 0.91-2.59 | .111 | — | — | — | ||||
— indicates we were unable to obtain estimate because cytogenetics had zero variance when added to the multivariate model.