FcγRIIa-131 and FcγRIIIa-158 genotypes and allele frequencies in control subjects, all HIT patients, and those who had undergone cardiopulmonary bypass (CPB)
. | Ab− group . | Ab+ group . | All HIT patients . | HIT patients after CPB . |
|---|---|---|---|---|
| FcγRIIa genotypes, no./total (%) | ||||
| HH | 20/86 (23.3) | 18/80 (22.5) | 28/99 (28.3) | 14/47 (29.8) |
| HR | 40/86 (46.5) | 37/80 (46.3) | 50/99 (50.5) | 23/47 (48.9) |
| RR | 26/86 (30.2) | 25/80 (31.2) | 21/99 (21.2) | 10/47 (21.3) |
| FcγRIIa alleles, frequency | ||||
| H131 | 0.465 | 0.457 | 0.535 | 0.543 |
| R131 | 0.535 | 0.543 | 0.465 | 0.457 |
| FcγRIIIa genotypes, no./total (%) | ||||
| VV | 14/86 (16.3) | 8/84 (9.5) | 22/102 (21.5) | 10/46 (21.7) |
| VF | 42/86 (48.8) | 41/84 (48.8) | 41/102 (40.2) | 21/46 (45.7) |
| FF | 30/86 (34.9) | 35/84 (41.7) | 39/102 (38.3) | 15/46 (32.6) |
| FcγRIIIa alleles, frequency | ||||
| V158 | 0.407 | 0.339 | 0.416 | 0.446 |
| F158 | 0.593 | 0.661 | 0.584 | 0.554 |
. | Ab− group . | Ab+ group . | All HIT patients . | HIT patients after CPB . |
|---|---|---|---|---|
| FcγRIIa genotypes, no./total (%) | ||||
| HH | 20/86 (23.3) | 18/80 (22.5) | 28/99 (28.3) | 14/47 (29.8) |
| HR | 40/86 (46.5) | 37/80 (46.3) | 50/99 (50.5) | 23/47 (48.9) |
| RR | 26/86 (30.2) | 25/80 (31.2) | 21/99 (21.2) | 10/47 (21.3) |
| FcγRIIa alleles, frequency | ||||
| H131 | 0.465 | 0.457 | 0.535 | 0.543 |
| R131 | 0.535 | 0.543 | 0.465 | 0.457 |
| FcγRIIIa genotypes, no./total (%) | ||||
| VV | 14/86 (16.3) | 8/84 (9.5) | 22/102 (21.5) | 10/46 (21.7) |
| VF | 42/86 (48.8) | 41/84 (48.8) | 41/102 (40.2) | 21/46 (45.7) |
| FF | 30/86 (34.9) | 35/84 (41.7) | 39/102 (38.3) | 15/46 (32.6) |
| FcγRIIIa alleles, frequency | ||||
| V158 | 0.407 | 0.339 | 0.416 | 0.446 |
| F158 | 0.593 | 0.661 | 0.584 | 0.554 |