Lack of Mcl-1 expression reduces the percentage of MEFs in S phase
.
Sub-G1
.
G1
.
G2
.
S
.
Mcl-1wt/wt
7 (3.5)
46.5 (4)
16.5 (7)
30 (3)
Mcl-1Δ/null
5 (3)
56 (4)
18 (3.5)
21 (1)
.
Sub-G1
.
G1
.
G2
.
S
.
Mcl-1wt/wt
7 (3.5)
46.5 (4)
16.5 (7)
30 (3)
Mcl-1Δ/null
5 (3)
56 (4)
18 (3.5)
21 (1)
Cell cycle analysis was performed on Mcl-1wt/wt and Mcl-1Δ/null MEFs using PI incorporation. The percentage of MEFs in each cell cycle phase is presented, with the SD in parentheses.