Table 1.

Genes induced or repressed by GATA-1: 3 hours


Probe

Gene

Description

Function

0 h → 3 h

SLR
94747_at  Csf2rb1  Colony-stimulating factor 2 receptor, beta 1   Signaling   32 → 514   4.3  
99922_at  Slc9a1  Solute carrier family 9, member 1   Membrane transporter   55 → 453   2.9  
94415_at  Bach1  BTB and CNC homology 1   Transcription factor   38 → 171   2.5  
94748_g_at  Csf2rb1  Colony-stimulating factor 2 receptor, beta 1   Signaling   111 → 402   1.9  
103210_at  Csf2rb2  Colony-stimulating factor 2 receptor, beta 2   Signaling   62 → 175   1.8  
103773_at  1110020K19Rik  RIKEN cDNA 1110020K19 gene   EST   192 → 773   1.7  
104283_at  4432405K22Rik  RIKEN cDNA 4432405K22 gene   EST   129 → 427   1.7  
97228_at  Lzf  Leucine zipper domain protein   Transcription factor?   125 → 505   1.6  
160225_at  Gtf2b  General transcription factor IIB   Transcription factor   409 → 1432   1.6  
98415_at  Crlf3  Cytokine receptor—like factor 3 (crème-9)   Signaling   384 → 1051   1.5  
102787_at  Gpr56  G protein—coupled receptor 56   Signaling   809 → 251   -1.6  
93836_at  Bnip3  BCL2/adenovirus E1B 19 kDa—interacting protein 1, NIP3   Apoptosis pathway   274 → 78   -1.7  
161067_at  Ifld2  Induced in fatty liver dystrophy 2   Apoptosis pathway   236 → 51   -1.7  
102789_at  Gata2  GATA-binding protein 2   Transcription factor   1909 → 454   -1.9  
104032_at  NO_GENE  Mus musculus, clone MGC:37981 IMAGE 5137303   EST   117 → 29   -1.9  
102397_at  Cbfa2t3h  Eto-2   Transcription factor   350 → 57   -2.1  
100468_g_at  Lyl1  Lymphoblastomic leukemia   Transcription factor   3505 → 793   -2.1  
100467_at  Lyl1  Lymphoblastomic leukemia   Transcription factor   1638 → 289   -2.3  
99603_g_at  Tieg  TGFB inducible early growth response 1   Transcription factor   108 → 21   -2.4  
92300_at  Mnt  Max binding protein   Transcription factor   113 → 16   -2.5  
102021_at  Il4ra  Interleukin 4 receptor, alpha   Signaling   142 → 22   -2.5  
100962_at
 
Nab2
 
Ngfi-A binding protein 2
 
Transcription factor
 
680 → 72
 
-3.1
 

Probe

Gene

Description

Function

0 h → 3 h

SLR
94747_at  Csf2rb1  Colony-stimulating factor 2 receptor, beta 1   Signaling   32 → 514   4.3  
99922_at  Slc9a1  Solute carrier family 9, member 1   Membrane transporter   55 → 453   2.9  
94415_at  Bach1  BTB and CNC homology 1   Transcription factor   38 → 171   2.5  
94748_g_at  Csf2rb1  Colony-stimulating factor 2 receptor, beta 1   Signaling   111 → 402   1.9  
103210_at  Csf2rb2  Colony-stimulating factor 2 receptor, beta 2   Signaling   62 → 175   1.8  
103773_at  1110020K19Rik  RIKEN cDNA 1110020K19 gene   EST   192 → 773   1.7  
104283_at  4432405K22Rik  RIKEN cDNA 4432405K22 gene   EST   129 → 427   1.7  
97228_at  Lzf  Leucine zipper domain protein   Transcription factor?   125 → 505   1.6  
160225_at  Gtf2b  General transcription factor IIB   Transcription factor   409 → 1432   1.6  
98415_at  Crlf3  Cytokine receptor—like factor 3 (crème-9)   Signaling   384 → 1051   1.5  
102787_at  Gpr56  G protein—coupled receptor 56   Signaling   809 → 251   -1.6  
93836_at  Bnip3  BCL2/adenovirus E1B 19 kDa—interacting protein 1, NIP3   Apoptosis pathway   274 → 78   -1.7  
161067_at  Ifld2  Induced in fatty liver dystrophy 2   Apoptosis pathway   236 → 51   -1.7  
102789_at  Gata2  GATA-binding protein 2   Transcription factor   1909 → 454   -1.9  
104032_at  NO_GENE  Mus musculus, clone MGC:37981 IMAGE 5137303   EST   117 → 29   -1.9  
102397_at  Cbfa2t3h  Eto-2   Transcription factor   350 → 57   -2.1  
100468_g_at  Lyl1  Lymphoblastomic leukemia   Transcription factor   3505 → 793   -2.1  
100467_at  Lyl1  Lymphoblastomic leukemia   Transcription factor   1638 → 289   -2.3  
99603_g_at  Tieg  TGFB inducible early growth response 1   Transcription factor   108 → 21   -2.4  
92300_at  Mnt  Max binding protein   Transcription factor   113 → 16   -2.5  
102021_at  Il4ra  Interleukin 4 receptor, alpha   Signaling   142 → 22   -2.5  
100962_at
 
Nab2
 
Ngfi-A binding protein 2
 
Transcription factor
 
680 → 72
 
-3.1
 

Microarray results were filtered at an SLR of 1.5, P < .005, and threshold of 100 for the 3-hour time points versus time 0. The penultimate column indicates signal values for the indicated time points (average for triplicate experiments). 3 versus 0; SLR = 1.5; threshold = 100; P < .005.

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