Table 4.

Impact of LD on outcome in cytogenetically defined subgroups



Analysis after induction therapy

Analysis after consolidation therapy
RFS
RFS
OS

P
RR (95% Cl)
P
RR (95% Cl)
P
RR (95% Cl)
Favorable karyotype   n.a.*  —   n.s.   —   n.s.   —  
Intermediate karyotype   .004   0.265 (0.107-0.653)   .006   0.460 (0.263-0.805)   .040   0.388 (0.157-0.959)  
Unfavorable karyotype
 
.030
 
0.330 (0.121-0.897)
 
.033
 
0.253 (0.072-0.892)
 
n.s.
 

 


Analysis after induction therapy

Analysis after consolidation therapy
RFS
RFS
OS

P
RR (95% Cl)
P
RR (95% Cl)
P
RR (95% Cl)
Favorable karyotype   n.a.*  —   n.s.   —   n.s.   —  
Intermediate karyotype   .004   0.265 (0.107-0.653)   .006   0.460 (0.263-0.805)   .040   0.388 (0.157-0.959)  
Unfavorable karyotype
 
.030
 
0.330 (0.121-0.897)
 
.033
 
0.253 (0.072-0.892)
 
n.s.
 

 

Abbreviations are explained in a footnote to Table 2.

*

No events occurred in patients with a favorable karyotype.

Since there was no overall correlation between LD after induction therapy and OS, the respective correlations within cytogenetically defined subgroups were not analyzed.

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