Table 3. Results of molecular genetic... | American Society of Hematology

Table 3.

Results of molecular genetic analysis of cases and tonsillar control

Case no. or control and nature of cells studied	FR2-JH	FR3-JH	DH-JH	Fr3-Jκ	Fr3-Jλ
Case 1
Whole section	P	P	P	P	P
Case 2
Whole section	P	P	P	P	P
Microdissected MZ B cells	P^*	P	P	P	P
Case 3
Whole section	P	P	P	P	P
Microdissected MZ B cells	P^*	P	P	P	P
Case 4
Whole section	P	P	P	P	P
Case 5
Whole section	P	P	P	P	P
Case 6
Whole section	Failed	P	Failed	P	P
Control tonsil
Whole section	P	P	P	P	P
Microdissected IEBCs	P†	P	P	P	P

Case no. or control and nature of cells studied	FR2-JH	FR3-JH	DH-JH	Fr3-Jκ	Fr3-Jλ
Case 1
Whole section	P	P	P	P	P
Case 2
Whole section	P	P	P	P	P
Microdissected MZ B cells	P^*	P	P	P	P
Case 3
Whole section	P	P	P	P	P
Microdissected MZ B cells	P^*	P	P	P	P
Case 4
Whole section	P	P	P	P	P
Case 5
Whole section	P	P	P	P	P
Case 6
Whole section	Failed	P	Failed	P	P
Control tonsil
Whole section	P	P	P	P	P
Microdissected IEBCs	P†	P	P	P	P

P indicates polyclonal; MZ, marginal zone; and IEBCs, intraepithelial B cells.

Cloning and sequencing show germ line configuration of the rearranged IgVH gene.

Cloning and sequencing show somatic mutation in the rearranged IgVH gene.