Expression of lineage-specific and differentiation markers on CD45+ cells harvested from NOD/SCID bone marrow
Patient no./recipient . | % human leukocytes CD45 . | % B lineage . | . | . | % progenitors CD34 . | % FISH-positive . | ||
---|---|---|---|---|---|---|---|---|
. | . | CD10 . | CD19 . | CD22 . | . | . | ||
CD34+/CD10- | ||||||||
9/1° | 35 | 83 | 87 | 56 | 88 | — | ||
9/2° | 46 | 85 | 90 | 58 | 83 | — | ||
10/1° | 28 | 88 | 92 | 80 | 72 | 89 | ||
10/2° | 25 | 92 | 90 | 77 | 80 | 90 | ||
43/1° | 6 | 87 | 96 | 60 | 93 | — | ||
43/2° | 2 | 91 | 92 | 58 | 89 | — | ||
47/1° | 20 | 84 | 88 | — | 80 | 100 | ||
47/2° | 28 | 87 | 80 | — | 73 | 100 | ||
CD34+/CD19- | ||||||||
9/1° | 12 | 86 | 91 | 63 | 85 | — | ||
9/2° | 15 | 80 | 83 | 55 | 83 | — | ||
10/1° | 79 | 92 | 95 | 84 | 90 | 91 | ||
10/2° | 82 | 90 | 97 | 80 | 86 | 100 | ||
25/1° | 95 | 78 | 80 | 75 | 79 | — | ||
25/2° | 95 | 82 | 85 | 80 | 75 | — |
Patient no./recipient . | % human leukocytes CD45 . | % B lineage . | . | . | % progenitors CD34 . | % FISH-positive . | ||
---|---|---|---|---|---|---|---|---|
. | . | CD10 . | CD19 . | CD22 . | . | . | ||
CD34+/CD10- | ||||||||
9/1° | 35 | 83 | 87 | 56 | 88 | — | ||
9/2° | 46 | 85 | 90 | 58 | 83 | — | ||
10/1° | 28 | 88 | 92 | 80 | 72 | 89 | ||
10/2° | 25 | 92 | 90 | 77 | 80 | 90 | ||
43/1° | 6 | 87 | 96 | 60 | 93 | — | ||
43/2° | 2 | 91 | 92 | 58 | 89 | — | ||
47/1° | 20 | 84 | 88 | — | 80 | 100 | ||
47/2° | 28 | 87 | 80 | — | 73 | 100 | ||
CD34+/CD19- | ||||||||
9/1° | 12 | 86 | 91 | 63 | 85 | — | ||
9/2° | 15 | 80 | 83 | 55 | 83 | — | ||
10/1° | 79 | 92 | 95 | 84 | 90 | 91 | ||
10/2° | 82 | 90 | 97 | 80 | 86 | 100 | ||
25/1° | 95 | 78 | 80 | 75 | 79 | — | ||
25/2° | 95 | 82 | 85 | 80 | 75 | — |
1° indicates primary NOD/SCID recipient; 2°, secondary NOD/SCID recipient; and —, not tested.