Table 1. Engraftment characteristics of... | American Society of Hematology

Table 1.

Engraftment characteristics of unsorted ALL cells in NOD/SCID mice

			% CD45⁺ in NOD/SCID^, by no. of unsorted cells injected*
Patient no.	Subtype	Karyotype	5 × 10⁵	10⁶	5 × 10⁶	10⁷	% FISH-positive
2	c-ALL†	Complex	—	—	1.9	3	100
9	pre-B	46,XX	—	—	13	—	—
10	c-ALL	t(12;21)	—	0	0.12	0.6	80
11	c-ALL	46,XX	0.16	0.3	8	—	—
18	c-ALL	46,XY	—	0.12	0.14	—	—
19	c-ALL	58,XY	—	—	0.15	—	80
21	pre-B	11q23	—	5	44	—	100
25	pre-B	46,XX	—	7	57	80	—
28	pre-B	46,XY	4	37	82	99	—
31	c-ALL	del(9p), del(17p)	59	80	92	98	> 90
32	pre-B	46,XY	—	0	0.13	—	—
43	pre-B	46,XX	—	—	0.6	—	—
47	c-ALL	del(17p)	—	—	9.2	24	100
53	pre-B	del(6p)	2.23	60	89	—	> 83
56	c-ALL	t(12;21)	—	3	—	11	> 70
69	c-ALL	t(12;21)	—	—	2	29	> 87

			% CD45⁺ in NOD/SCID^, by no. of unsorted cells injected*
Patient no.	Subtype	Karyotype	5 × 10⁵	10⁶	5 × 10⁶	10⁷	% FISH-positive
2	c-ALL†	Complex	—	—	1.9	3	100
9	pre-B	46,XX	—	—	13	—	—
10	c-ALL	t(12;21)	—	0	0.12	0.6	80
11	c-ALL	46,XX	0.16	0.3	8	—	—
18	c-ALL	46,XY	—	0.12	0.14	—	—
19	c-ALL	58,XY	—	—	0.15	—	80
21	pre-B	11q23	—	5	44	—	100
25	pre-B	46,XX	—	7	57	80	—
28	pre-B	46,XY	4	37	82	99	—
31	c-ALL	del(9p), del(17p)	59	80	92	98	> 90
32	pre-B	46,XY	—	0	0.13	—	—
43	pre-B	46,XX	—	—	0.6	—	—
47	c-ALL	del(17p)	—	—	9.2	24	100
53	pre-B	del(6p)	2.23	60	89	—	> 83
56	c-ALL	t(12;21)	—	3	—	11	> 70
69	c-ALL	t(12;21)	—	—	2	29	> 87

— indicates not tested.

Each value represents the mean level of CD45⁺ cells in the femoral marrow of at least 2 NOD/SCID mice

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