Death and surgical complications caused by splenectomy for ITP
. | Laparotomy . | Laparoscopy . |
|---|---|---|
| Death* | ||
| Articles, no. | 81 | 29 |
| Mortality rate, % (no. patients who died/total no. evaluable patients) | 1 (48/4955) | 0.2 (3/1301) |
| Causes of death | ||
| Postoperative bleeding, no. | 11 | 1 (intraabdominal) |
| Gastrointestinal, no. | 5 | — |
| Intracranial, no. | 5 | — |
| Not specified, no. | 1 | — |
| Cardiovascular, no. | 10 | 1 (aortic aneurysm) |
| Cardiac, no. | 7 | — |
| Stroke, no. | 2 | — |
| Aortic aneurysm, no. | 1 | — |
| Infectious, no. | 6 | 1 (sepsis) |
| Pneumonia, no. | 2 | — |
| Sepsis, no. | 2 | — |
| Subdiaphragmatic abscess, no. | 1 | — |
| Viral hepatitis, no. | 1 | — |
| Venous thromboembolism, no. | 5 | — |
| Pancreatitis, no. | 3 | — |
| Miscellaneous, no. | 3 | — |
| Not reported, no. | 10 | — |
| Complications* | ||
| Articles, no. | 35 | 19 |
| Complication rate, % (no. patients with complications/total no. evaluable patients) | 12.9 (318/2465) | 9.6 (88/921) |
. | Laparotomy . | Laparoscopy . |
|---|---|---|
| Death* | ||
| Articles, no. | 81 | 29 |
| Mortality rate, % (no. patients who died/total no. evaluable patients) | 1 (48/4955) | 0.2 (3/1301) |
| Causes of death | ||
| Postoperative bleeding, no. | 11 | 1 (intraabdominal) |
| Gastrointestinal, no. | 5 | — |
| Intracranial, no. | 5 | — |
| Not specified, no. | 1 | — |
| Cardiovascular, no. | 10 | 1 (aortic aneurysm) |
| Cardiac, no. | 7 | — |
| Stroke, no. | 2 | — |
| Aortic aneurysm, no. | 1 | — |
| Infectious, no. | 6 | 1 (sepsis) |
| Pneumonia, no. | 2 | — |
| Sepsis, no. | 2 | — |
| Subdiaphragmatic abscess, no. | 1 | — |
| Viral hepatitis, no. | 1 | — |
| Venous thromboembolism, no. | 5 | — |
| Pancreatitis, no. | 3 | — |
| Miscellaneous, no. | 3 | — |
| Not reported, no. | 10 | — |
| Complications* | ||
| Articles, no. | 35 | 19 |
| Complication rate, % (no. patients with complications/total no. evaluable patients) | 12.9 (318/2465) | 9.6 (88/921) |
Death and complications from splenectomy. Data are reported separately for open laparotomy and laparoscopic splenectomy. Data from case series of adults only and adults plus children were combined for this analysis. Miscellaneous causes of death included respiratory failure, hepatic or renal failure, and gastric perforation. Not all articles for which mortality could be assessed reported the cause of death or the rate of complications.—indicates that no deaths from this cause were reported.
P = .008