Characteristics of 275 children with ETV6/RUNX1+ or ETV6/RUNX1- precursor B-ALL tested for in vitro cellular drug resistance
ETV6/RUNX1 . | Positive . | Negative . | P . |
|---|---|---|---|
| No. of patients | 83 | 192 | |
| Median age, y (range) | 4.4 (1.3-15.6) | 5.1 (1.1-17.0) | .042 |
| Sex | .85 | ||
| Male, n (%) | 46 (55) | 104 (54) | |
| Female, n (%) | 37 (45) | 88 (46) | |
| WBC count | |||
| Median | 8 | 7 | .45 |
| Less than 10 × 109/L, n (%) | 46 (55) | 115 (60) | |
| Between 10 and 50 × 109/L, n (%) | 29 (35) | 57 (30) | |
| 50 × 109/L or more, n (%) | 8 (10) | 20 (10) | |
| Modal number | .001 | ||
| 45-46, n (%) | 41 (49) | 58 (30) | |
| 47-51, n (%) | 15 (18) | 21 (11) | |
| 52-60, n (%) | 0 (0) | 76 (40) | |
| More than 60, n (%) | 0 (0) | 5 (2) | |
| Unknown, n (%) | 27 (33) | 32 (17) |
ETV6/RUNX1 . | Positive . | Negative . | P . |
|---|---|---|---|
| No. of patients | 83 | 192 | |
| Median age, y (range) | 4.4 (1.3-15.6) | 5.1 (1.1-17.0) | .042 |
| Sex | .85 | ||
| Male, n (%) | 46 (55) | 104 (54) | |
| Female, n (%) | 37 (45) | 88 (46) | |
| WBC count | |||
| Median | 8 | 7 | .45 |
| Less than 10 × 109/L, n (%) | 46 (55) | 115 (60) | |
| Between 10 and 50 × 109/L, n (%) | 29 (35) | 57 (30) | |
| 50 × 109/L or more, n (%) | 8 (10) | 20 (10) | |
| Modal number | .001 | ||
| 45-46, n (%) | 41 (49) | 58 (30) | |
| 47-51, n (%) | 15 (18) | 21 (11) | |
| 52-60, n (%) | 0 (0) | 76 (40) | |
| More than 60, n (%) | 0 (0) | 5 (2) | |
| Unknown, n (%) | 27 (33) | 32 (17) |
P values were determined by χ2 and Mann-Whitney U test.