Histologic findings
. | Patient no. 1 . | . | Patient no. 2 . | . | Patient no. 3 . | . | Patient no. 4 . | . | Patient no. 5 . | . | Patient no. 6 . | . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
. | A . | B . | A . | B . | A . | B . | A . | B . | A . | B . | A . | B . | ||||||
| Epidermal involvement | 2 | 0 | 1 | 0 | 2 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | ||||||
| Infiltrate | 1 | 0 | 1 | 1 | 2 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | ||||||
| Superficial macrophages | 2 | 2 | 2 | 2 | 2 | 1 | 2 | 1 | 0 | 0 | 1 | 0 | ||||||
| Deep macrophages | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | ||||||
| Superficial dermal sclerosis | 0 | 0 | 0 | 0 | 2 | 1 | 2 | 1 | 2 | 2 | 3 | 1 | ||||||
| Deep dermal sclerosis | 0 | 0 | 0 | 0 | 3 | 3 | 2 | 2 | 2 | 2 | 3 | 3 | ||||||
. | Patient no. 1 . | . | Patient no. 2 . | . | Patient no. 3 . | . | Patient no. 4 . | . | Patient no. 5 . | . | Patient no. 6 . | . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
. | A . | B . | A . | B . | A . | B . | A . | B . | A . | B . | A . | B . | ||||||
| Epidermal involvement | 2 | 0 | 1 | 0 | 2 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | ||||||
| Infiltrate | 1 | 0 | 1 | 1 | 2 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | ||||||
| Superficial macrophages | 2 | 2 | 2 | 2 | 2 | 1 | 2 | 1 | 0 | 0 | 1 | 0 | ||||||
| Deep macrophages | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | ||||||
| Superficial dermal sclerosis | 0 | 0 | 0 | 0 | 2 | 1 | 2 | 1 | 2 | 2 | 3 | 1 | ||||||
| Deep dermal sclerosis | 0 | 0 | 0 | 0 | 3 | 3 | 2 | 2 | 2 | 2 | 3 | 3 | ||||||
A indicates before treatment; B, after treatment.
Epidermal involvement: 0 indicates no epidermal involvement; 1, vacuolar changes of basal keratinocytes; 2, dyskeratotic cells in the epidermis.
Infiltrate: 0 indicates no lymphocytic infiltrate in the upper dermis; 1, mild lymphocytic infiltrate in the upper dermis; 2, moderate lymphocytic infiltrate in the upper dermis; 3, severe lymphocytic infiltrate in the upper dermis.
Macrophages: 0 indicates almost no macrophages (superficial or deep); 1, mild amount of macrophages (superficial or deep); 2, moderate amount of macrophages (superficial or deep).
Dermal sclerosis: 0 indicates normal collagen bundles; 1, thickened, compact collagen (mild); 2, thickened, compact collagen (moderate); 3, thickened, compact collagen (severe).