Evidence for elevated levels of certain chemoattractants in ischemic areas of diseases where macrophages have been found to accumulate in vivo
. | Dermal sounds . | Atherosclerosis . | Rheumatoid arthritis . | Proliferative retinopathy . |
|---|---|---|---|---|
| CC chemokines | Y (Heinrich et al137 ) | Y (Burke-Gaffney et al138 , Linton and Fazio139 ) | Y (DeVries et al140 , Bodolay et al141 ) | Y (Capeans et al142 , Abu el-Asrar et al143 ) |
| CXCL12 | ND | ND | Y (Pufe et al144 ) | ND |
| VEGF | Y (Dvorak et al145 ) | Y (Inoue et al146 ) | Y (Pufe et al144 , Afuwape et al147 ) | Y (Ishida et al148 ) |
| CSF-1 | Y (Wu et al149 ) | Y (Clinton et al150 , Qiao et al151 ) | Y (Seitz et al152 ) | Y (Elner et al153 ) |
| EMAP II | ND | ND | ND | ND |
| Endothelin | Y (Black et al154 , Lipa et al155 ) | Y (Fan et al156 , Best et al157 ) | Y (Haq et al158 ) | Y (Oku et al159 ) |
. | Dermal sounds . | Atherosclerosis . | Rheumatoid arthritis . | Proliferative retinopathy . |
|---|---|---|---|---|
| CC chemokines | Y (Heinrich et al137 ) | Y (Burke-Gaffney et al138 , Linton and Fazio139 ) | Y (DeVries et al140 , Bodolay et al141 ) | Y (Capeans et al142 , Abu el-Asrar et al143 ) |
| CXCL12 | ND | ND | Y (Pufe et al144 ) | ND |
| VEGF | Y (Dvorak et al145 ) | Y (Inoue et al146 ) | Y (Pufe et al144 , Afuwape et al147 ) | Y (Ishida et al148 ) |
| CSF-1 | Y (Wu et al149 ) | Y (Clinton et al150 , Qiao et al151 ) | Y (Seitz et al152 ) | Y (Elner et al153 ) |
| EMAP II | ND | ND | ND | ND |
| Endothelin | Y (Black et al154 , Lipa et al155 ) | Y (Fan et al156 , Best et al157 ) | Y (Haq et al158 ) | Y (Oku et al159 ) |
Data in parentheses are references.
Y indicates elevated levels observed; and ND, not determined.