Table 1.

Predicted A*1-and A*24-restricted epitope peptides


Amino acid position

Peptide sequence
A*1 peptides*  
    aa 70-78   PVDREDTAY  
    aa 72-80   DREDTAYSY  
    aa 93-101   VLDMASTSF  
    aa 226-234   KTTPMKPCY  
    aa 287-295   YSEDVDIET  
    aa 294-302   ETPDTHISY  
    aa 318-326   QSMPNRPNY  
    aa 405-413   GTEDELPNY  
    aa 479-487   LYLPDKLKY  
    aa 573-581   LLLPGSYTY  
    aa 638-646   TNDQSFNDY  
    aa 699-707   YTYSGSIPY  
    aa 886-894   TDLGQNLLY  
    aa 906-914   EVDPMDEPT  
    aa 909-917   PMDEPTLLY  
A*24 peptides  
    aa 37-45   TYFSLNNKF  
    aa 369-377   SYQLLLDSI  
    aa 393-401   SYDPDVRII  
    aa 473-481   LYSNIALYL  
    aa 471-479   NFLYSNIAL  
    aa 527-535
 
DYMDNVNPF
 

Amino acid position

Peptide sequence
A*1 peptides*  
    aa 70-78   PVDREDTAY  
    aa 72-80   DREDTAYSY  
    aa 93-101   VLDMASTSF  
    aa 226-234   KTTPMKPCY  
    aa 287-295   YSEDVDIET  
    aa 294-302   ETPDTHISY  
    aa 318-326   QSMPNRPNY  
    aa 405-413   GTEDELPNY  
    aa 479-487   LYLPDKLKY  
    aa 573-581   LLLPGSYTY  
    aa 638-646   TNDQSFNDY  
    aa 699-707   YTYSGSIPY  
    aa 886-894   TDLGQNLLY  
    aa 906-914   EVDPMDEPT  
    aa 909-917   PMDEPTLLY  
A*24 peptides  
    aa 37-45   TYFSLNNKF  
    aa 369-377   SYQLLLDSI  
    aa 393-401   SYDPDVRII  
    aa 473-481   LYSNIALYL  
    aa 471-479   NFLYSNIAL  
    aa 527-535
 
DYMDNVNPF
 
*

Fifteen potential hexon-specific peptides were synthesized to identify the peptide epitope presented in the context of the A*1 allele.

Six potential hexon-specific peptides were synthesized to identify the peptide epitope presented in the context of the A*24 allele.

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