Gene expression changes in mature DCs after treatment with ABT-627, an endothelin A receptor antagonist
Gene description . | Fold change expression . |
|---|---|
| Increased expression | |
| Caspase-5 | 19.60 |
| IL-10 | 6.25 |
| Caspase-2 | 5.20 |
| P53 regulated apoptosis inducing protein mRNA | 5.03 |
| Death receptor 3 | 3.90 |
| Caspase-8 | 3.89 |
| Apoptotic protease activating factor 1 (ARAF 1) | 3.57 |
| Caspase recruitment domain protein 10 mRNA | 3.28 |
| Decreased expression | |
| Interferon-α1 | 19.79 |
| Mature T-cell proliferation 1 protein mRNA | 6.50 |
| IL-12A | 4.28 |
| IL-12 receptor | 4.01 |
| MHC class II | 3.72 |
Gene description . | Fold change expression . |
|---|---|
| Increased expression | |
| Caspase-5 | 19.60 |
| IL-10 | 6.25 |
| Caspase-2 | 5.20 |
| P53 regulated apoptosis inducing protein mRNA | 5.03 |
| Death receptor 3 | 3.90 |
| Caspase-8 | 3.89 |
| Apoptotic protease activating factor 1 (ARAF 1) | 3.57 |
| Caspase recruitment domain protein 10 mRNA | 3.28 |
| Decreased expression | |
| Interferon-α1 | 19.79 |
| Mature T-cell proliferation 1 protein mRNA | 6.50 |
| IL-12A | 4.28 |
| IL-12 receptor | 4.01 |
| MHC class II | 3.72 |